KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C5orf22
All Species:
8.79
Human Site:
Y435
Identified Species:
21.48
UniProt:
Q49AR2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49AR2
NP_060826.2
442
49967
Y435
G
N
L
D
L
Q
V
Y
A
A
E
S
P
P
S
Chimpanzee
Pan troglodytes
XP_517821
442
49983
Y435
G
N
L
D
L
Q
V
Y
A
A
E
S
P
P
S
Rhesus Macaque
Macaca mulatta
XP_001086409
442
50107
Y435
G
N
L
D
L
Q
V
Y
A
A
E
S
S
P
S
Dog
Lupus familis
XP_855465
482
54089
V474
G
A
V
D
I
H
L
V
Y
L
A
E
C
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC1
442
49411
V434
G
T
L
D
T
H
L
V
Y
S
E
E
S
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418996
538
59622
D530
G
T
L
D
V
H
L
D
Y
S
S
N
S
S
S
Frog
Xenopus laevis
Q6PAE6
423
47851
E415
G
S
L
D
V
H
L
E
F
S
P
G
S
S
S
Zebra Danio
Brachydanio rerio
Q7SZF1
439
49547
D426
G
C
L
D
V
H
R
D
Y
E
S
I
P
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524154
470
53922
A456
G
E
R
L
H
D
K
A
I
L
H
Y
M
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781846
578
64288
H571
L
Y
N
Q
L
D
V
H
I
E
Y
E
L
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.2
82.5
N.A.
78.5
N.A.
N.A.
N.A.
55.3
62.4
54.7
N.A.
22.5
N.A.
N.A.
36.1
Protein Similarity:
100
99.7
98.8
86.7
N.A.
86.1
N.A.
N.A.
N.A.
65.6
75.5
69.4
N.A.
37.6
N.A.
N.A.
52.4
P-Site Identity:
100
100
93.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
26.6
26.6
26.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
33.3
N.A.
46.6
N.A.
N.A.
N.A.
53.3
53.3
33.3
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
30
30
10
0
0
20
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
80
0
20
0
20
0
0
0
0
0
10
10
% D
% Glu:
0
10
0
0
0
0
0
10
0
20
40
30
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
90
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
50
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
20
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
70
10
40
0
40
0
0
20
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
30
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
30
40
10
% P
% Gln:
0
0
0
10
0
30
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
30
20
30
40
30
50
% S
% Thr:
0
20
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
30
0
40
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
30
40
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _