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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERKL All Species: 2.73
Human Site: S214 Identified Species: 7.5
UniProt: Q49MI3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q49MI3 NP_001025482.1 558 62622 S214 E Y E G H A L S L L K E C E L
Chimpanzee Pan troglodytes XP_515955 494 55390 Q176 L K I L L N P Q S H K K E A T
Rhesus Macaque Macaca mulatta XP_001111087 537 59920 V192 I D K Y D G I V C V G G D G M
Dog Lupus familis XP_545552 507 55866 P186 I Y H E K V E P L L R V A G I
Cat Felis silvestris
Mouse Mus musculus Q8K4Q7 531 59793 V192 T D S Y D G I V C V G G D G M
Rat Rattus norvegicus NP_001128333 531 59635 V192 T D S Y D G I V C V G G D G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515880 482 53692 L164 A G H A L S L L K E C D L Q E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391867 431 48985 C112 T D F H A V V C I G G D G T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797972 615 68589 S202 E G P D H A K S L M Q M M D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.8 23.1 75 N.A. 20.7 22.2 N.A. 60.2 N.A. N.A. N.A. N.A. N.A. 24.3 N.A. 26.6
Protein Similarity: 100 88.1 41.5 80.4 N.A. 40.1 41 N.A. 68.6 N.A. N.A. N.A. N.A. N.A. 42.4 N.A. 44.5
P-Site Identity: 100 6.6 0 20 N.A. 0 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 40
P-Site Similarity: 100 13.3 26.6 33.3 N.A. 20 20 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. 26.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 12 23 0 0 0 0 0 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 12 34 0 12 0 12 0 0 % C
% Asp: 0 45 0 12 34 0 0 0 0 0 0 23 34 12 0 % D
% Glu: 23 0 12 12 0 0 12 0 0 12 0 12 12 12 12 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 23 0 12 0 34 0 0 0 12 45 34 12 45 0 % G
% His: 0 0 23 12 23 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 23 0 12 0 0 0 34 0 12 0 0 0 0 0 12 % I
% Lys: 0 12 12 0 12 0 12 0 12 0 23 12 0 0 0 % K
% Leu: 12 0 0 12 23 0 23 12 34 23 0 0 12 0 34 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 12 12 0 34 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 0 12 12 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 12 0 0 12 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 0 0 23 0 0 12 0 23 12 0 0 0 0 0 0 % S
% Thr: 34 0 0 0 0 0 0 0 0 0 0 0 0 12 12 % T
% Val: 0 0 0 0 0 23 12 34 0 34 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 34 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _