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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERKL
All Species:
1.52
Human Site:
T515
Identified Species:
4.17
UniProt:
Q49MI3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49MI3
NP_001025482.1
558
62622
T515
P
E
E
E
E
D
E
T
A
S
E
N
C
F
P
Chimpanzee
Pan troglodytes
XP_515955
494
55390
S454
N
T
R
L
N
N
G
S
M
A
L
I
I
A
R
Rhesus Macaque
Macaca mulatta
XP_001111087
537
59920
K478
D
L
K
E
E
G
K
K
R
F
G
H
I
C
S
Dog
Lupus familis
XP_545552
507
55866
V465
Y
T
V
G
E
V
K
V
R
P
R
N
N
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q7
531
59793
Q478
D
S
K
E
Q
E
K
Q
K
F
G
K
I
C
K
Rat
Rattus norvegicus
NP_001128333
531
59635
Q478
D
L
K
E
L
E
K
Q
K
F
G
Q
I
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515880
482
53692
I442
E
N
N
H
L
W
N
I
D
G
D
L
M
E
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391867
431
48985
S390
R
Y
M
S
S
N
L
S
V
W
N
C
D
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797972
615
68589
V502
M
V
A
E
P
S
N
V
E
N
E
Q
Q
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.8
23.1
75
N.A.
20.7
22.2
N.A.
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
26.6
Protein Similarity:
100
88.1
41.5
80.4
N.A.
40.1
41
N.A.
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
44.5
P-Site Identity:
100
0
13.3
13.3
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
20
33.3
20
N.A.
33.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
12
12
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
12
34
0
% C
% Asp:
34
0
0
0
0
12
0
0
12
0
12
0
12
0
0
% D
% Glu:
12
12
12
56
34
23
12
0
12
0
23
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
34
0
0
0
12
12
% F
% Gly:
0
0
0
12
0
12
12
0
0
12
34
0
0
12
12
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
12
45
0
0
% I
% Lys:
0
0
34
0
0
0
45
12
23
0
0
12
0
0
23
% K
% Leu:
0
23
0
12
23
0
12
0
0
0
12
12
0
0
0
% L
% Met:
12
0
12
0
0
0
0
0
12
0
0
0
12
0
0
% M
% Asn:
12
12
12
0
12
23
23
0
0
12
12
23
12
0
0
% N
% Pro:
12
0
0
0
12
0
0
0
0
12
0
0
0
0
12
% P
% Gln:
0
0
0
0
12
0
0
23
0
0
0
23
12
0
0
% Q
% Arg:
12
0
12
0
0
0
0
0
23
0
12
0
0
0
12
% R
% Ser:
0
12
0
12
12
12
0
23
0
12
0
0
0
12
12
% S
% Thr:
0
23
0
0
0
0
0
12
0
0
0
0
0
12
0
% T
% Val:
0
12
12
0
0
12
0
23
12
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _