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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERKL
All Species:
2.73
Human Site:
Y187
Identified Species:
7.5
UniProt:
Q49MI3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q49MI3
NP_001025482.1
558
62622
Y187
K
E
A
T
Q
V
Y
Y
E
K
V
E
P
L
L
Chimpanzee
Pan troglodytes
XP_515955
494
55390
D149
N
L
S
E
D
H
C
D
I
W
F
R
Q
F
K
Rhesus Macaque
Macaca mulatta
XP_001111087
537
59920
T165
F
T
L
A
S
I
T
T
D
I
I
V
T
E
H
Dog
Lupus familis
XP_545552
507
55866
R159
I
L
A
G
F
S
N
R
P
K
S
L
K
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q7
531
59793
T165
F
T
L
A
S
I
T
T
E
I
I
I
T
E
H
Rat
Rattus norvegicus
NP_001128333
531
59635
T165
F
T
L
A
S
I
T
T
E
I
I
I
T
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515880
482
53692
K137
A
T
Q
V
Y
Y
E
K
V
A
P
L
L
H
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391867
431
48985
K85
T
I
A
G
I
E
T
K
M
L
V
T
E
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797972
615
68589
D175
G
K
G
Q
S
V
Y
D
I
K
V
A
P
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.8
23.1
75
N.A.
20.7
22.2
N.A.
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
26.6
Protein Similarity:
100
88.1
41.5
80.4
N.A.
40.1
41
N.A.
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
42.4
N.A.
44.5
P-Site Identity:
100
0
0
13.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
40
P-Site Similarity:
100
6.6
20
26.6
N.A.
20
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
34
34
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
23
12
0
0
0
0
0
0
% D
% Glu:
0
12
0
12
0
12
12
0
34
0
0
12
12
34
0
% E
% Phe:
34
0
0
0
12
0
0
0
0
0
12
0
0
12
12
% F
% Gly:
12
0
12
23
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
34
% H
% Ile:
12
12
0
0
12
34
0
0
23
34
34
23
0
0
12
% I
% Lys:
12
12
0
0
0
0
0
23
0
34
0
0
12
0
12
% K
% Leu:
0
23
34
0
0
0
0
0
0
12
0
23
12
23
23
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
12
0
23
0
0
% P
% Gln:
0
0
12
12
12
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
12
0
12
0
% R
% Ser:
0
0
12
0
45
12
0
0
0
0
12
0
0
0
0
% S
% Thr:
12
45
0
12
0
0
45
34
0
0
0
12
34
0
0
% T
% Val:
0
0
0
12
0
23
0
0
12
0
34
12
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
12
23
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _