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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C2CD3 All Species: 7.58
Human Site: S1885 Identified Species: 18.52
UniProt: Q4AC94 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4AC94 NP_056346.3 2353 260349 S1885 S Q T S I L T S L R K N L S E
Chimpanzee Pan troglodytes XP_001174891 2353 260095 S1885 S Q T S I L T S L R K N L S E
Rhesus Macaque Macaca mulatta XP_001115612 2242 248481 L1782 L R K N L S E L D Q I Q R Y F
Dog Lupus familis XP_534012 2030 226571 I1570 F R E E R L E I Q V W R A Y G
Cat Felis silvestris
Mouse Mus musculus Q52KB6 2323 255255 L1863 S S S H T S I L T S L R K N L
Rat Rattus norvegicus XP_001066026 2319 255216 C1859 P H T S I L T C L R K N L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519708 2304 248741 L1838 G V R G D I R L E S L S H S S
Chicken Gallus gallus XP_417250 1898 210092 D1438 L I G S A Y V D L R A L A E R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001337534 2147 238438 R1687 T P P E H L E R L L S D R S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781752 2326 256604 T1863 S S S Y L L E T F R K N M E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 91.3 70.9 N.A. 75.8 75.1 N.A. 50.7 46.5 N.A. 39.7 N.A. N.A. N.A. N.A. 27.2
Protein Similarity: 100 99.3 92.8 75.8 N.A. 84.6 83.6 N.A. 64.6 59.4 N.A. 56 N.A. N.A. N.A. N.A. 45.1
P-Site Identity: 100 100 0 6.6 N.A. 6.6 80 N.A. 6.6 20 N.A. 20 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 26.6 13.3 N.A. 20 80 N.A. 20 20 N.A. 33.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 10 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 10 0 0 10 0 0 0 % D
% Glu: 0 0 10 20 0 0 40 0 10 0 0 0 0 20 40 % E
% Phe: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % F
% Gly: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 10 0 10 10 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 10 0 0 30 10 10 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 40 0 10 0 0 % K
% Leu: 20 0 0 0 20 60 0 30 50 10 20 10 30 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 40 0 10 0 % N
% Pro: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 0 0 0 0 10 10 0 10 0 0 0 % Q
% Arg: 0 20 10 0 10 0 10 10 0 50 0 20 20 0 10 % R
% Ser: 40 20 20 40 0 20 0 20 0 20 10 10 0 50 20 % S
% Thr: 10 0 30 0 10 0 30 10 10 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 10 0 10 0 0 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _