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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C2CD3 All Species: 5.15
Human Site: S2328 Identified Species: 12.59
UniProt: Q4AC94 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4AC94 NP_056346.3 2353 260349 S2328 P C R P R P N S L P L N L P E
Chimpanzee Pan troglodytes XP_001174891 2353 260095 S2328 P C R P R P N S L P P N L P E
Rhesus Macaque Macaca mulatta XP_001115612 2242 248481 L2218 C R P R P N S L P P N L P E E
Dog Lupus familis XP_534012 2030 226571 P2006 P K D S S L D P E S Q C I L E
Cat Felis silvestris
Mouse Mus musculus Q52KB6 2323 255255 N2299 R P Y S I P P N L P E E E T R
Rat Rattus norvegicus XP_001066026 2319 255216 N2295 R P Y S L P P N L P E E E T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519708 2304 248741 Q2279 R S R P K P S Q A P A D L P Q
Chicken Gallus gallus XP_417250 1898 210092 V1874 P Q Q R P A L V P A E L S E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001337534 2147 238438 I2123 K P R S R P S I P P S Q R S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781752 2326 256604 T2301 R S Q A A S R T T L P F S Y K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 91.3 70.9 N.A. 75.8 75.1 N.A. 50.7 46.5 N.A. 39.7 N.A. N.A. N.A. N.A. 27.2
Protein Similarity: 100 99.3 92.8 75.8 N.A. 84.6 83.6 N.A. 64.6 59.4 N.A. 56 N.A. N.A. N.A. N.A. 45.1
P-Site Identity: 100 93.3 13.3 13.3 N.A. 20 20 N.A. 40 13.3 N.A. 33.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 20 26.6 N.A. 26.6 26.6 N.A. 66.6 20 N.A. 40 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 0 10 10 10 0 0 0 0 % A
% Cys: 10 20 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 30 20 20 20 60 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 0 0 0 10 0 0 % I
% Lys: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 10 10 10 10 40 10 10 20 30 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 20 20 0 0 10 20 0 0 0 % N
% Pro: 40 30 10 30 20 60 20 10 30 70 20 0 10 30 0 % P
% Gln: 0 10 20 0 0 0 0 10 0 0 10 10 0 0 10 % Q
% Arg: 40 10 40 20 30 0 10 0 0 0 0 0 10 0 20 % R
% Ser: 0 20 0 40 10 10 30 20 0 10 10 0 20 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 10 0 0 0 0 20 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _