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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2CD3
All Species:
6.97
Human Site:
S435
Identified Species:
17.04
UniProt:
Q4AC94
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4AC94
NP_056346.3
2353
260349
S435
G
S
D
V
Y
C
I
S
E
L
N
D
P
Q
Y
Chimpanzee
Pan troglodytes
XP_001174891
2353
260095
S435
G
S
D
V
Y
C
I
S
E
L
N
D
P
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001115612
2242
248481
M414
T
P
E
D
T
Q
T
M
T
L
S
V
D
R
L
Dog
Lupus familis
XP_534012
2030
226571
L202
V
I
T
K
L
D
H
L
P
I
G
R
V
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q52KB6
2323
255255
L434
P
Q
Y
D
Q
S
L
L
E
N
L
F
Y
T
V
Rat
Rattus norvegicus
XP_001066026
2319
255216
E435
Q
Y
D
Q
S
L
L
E
N
L
F
Y
T
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519708
2304
248741
Y433
L
F
Y
T
A
P
K
Y
D
V
S
M
S
D
F
Chicken
Gallus gallus
XP_417250
1898
210092
G70
L
V
R
L
R
W
W
G
E
T
S
D
G
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337534
2147
238438
E319
L
E
N
I
L
Q
S
E
I
Q
L
P
A
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781752
2326
256604
S456
S
G
S
L
S
L
S
S
S
R
D
A
S
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.3
70.9
N.A.
75.8
75.1
N.A.
50.7
46.5
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
99.3
92.8
75.8
N.A.
84.6
83.6
N.A.
64.6
59.4
N.A.
56
N.A.
N.A.
N.A.
N.A.
45.1
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
13.3
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
13.3
N.A.
13.3
20
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
20
0
10
0
0
10
0
10
30
10
10
10
% D
% Glu:
0
10
10
0
0
0
0
20
40
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
10
% F
% Gly:
20
10
0
0
0
0
0
10
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
0
0
20
0
10
10
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
30
0
0
20
20
20
20
20
0
40
20
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
10
20
0
0
0
0
% N
% Pro:
10
10
0
0
0
10
0
0
10
0
0
10
20
0
10
% P
% Gln:
10
10
0
10
10
20
0
0
0
10
0
0
0
40
0
% Q
% Arg:
0
0
10
0
10
0
0
0
0
10
0
10
0
10
0
% R
% Ser:
10
20
10
0
20
10
20
30
10
0
30
0
20
0
0
% S
% Thr:
10
0
10
10
10
0
10
0
10
10
0
0
10
20
0
% T
% Val:
10
10
0
20
0
0
0
0
0
10
0
10
10
10
20
% V
% Trp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
20
0
20
0
0
10
0
0
0
10
10
10
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _