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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2CD3
All Species:
4.85
Human Site:
S493
Identified Species:
11.85
UniProt:
Q4AC94
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4AC94
NP_056346.3
2353
260349
S493
S
S
K
V
L
E
S
S
D
H
K
L
K
K
R
Chimpanzee
Pan troglodytes
XP_001174891
2353
260095
S493
S
S
K
V
L
E
S
S
D
H
K
L
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001115612
2242
248481
Y472
K
R
T
F
F
V
E
Y
H
F
P
V
G
F
S
Dog
Lupus familis
XP_534012
2030
226571
P260
S
Y
N
P
L
P
T
P
D
V
T
E
N
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q52KB6
2323
255255
R492
R
A
A
V
K
K
S
R
N
P
I
D
Q
Q
E
Rat
Rattus norvegicus
XP_001066026
2319
255216
R493
R
A
A
V
K
K
S
R
N
A
A
M
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519708
2304
248741
A491
N
C
S
V
G
R
K
A
T
S
K
I
P
E
E
Chicken
Gallus gallus
XP_417250
1898
210092
V128
D
R
L
P
V
G
R
V
Q
I
T
E
L
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337534
2147
238438
A377
W
D
G
E
G
S
L
A
D
S
L
S
D
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781752
2326
256604
G514
I
P
V
R
T
G
K
G
V
D
Q
R
G
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.3
70.9
N.A.
75.8
75.1
N.A.
50.7
46.5
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
99.3
92.8
75.8
N.A.
84.6
83.6
N.A.
64.6
59.4
N.A.
56
N.A.
N.A.
N.A.
N.A.
45.1
P-Site Identity:
100
100
0
20
N.A.
13.3
13.3
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
26.6
N.A.
46.6
40
N.A.
40
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
0
0
0
20
0
10
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
40
10
0
10
10
0
0
% D
% Glu:
0
0
0
10
0
20
10
0
0
0
0
20
0
10
20
% E
% Phe:
0
0
0
10
10
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
10
0
20
20
0
10
0
0
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
20
0
0
0
10
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% I
% Lys:
10
0
20
0
20
20
20
0
0
0
30
0
20
20
0
% K
% Leu:
0
0
10
0
30
0
10
0
0
0
10
20
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
20
0
0
0
10
0
0
% N
% Pro:
0
10
0
20
0
10
0
10
0
10
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
10
10
10
% Q
% Arg:
20
20
0
10
0
10
10
20
0
0
0
10
0
0
30
% R
% Ser:
30
20
10
0
0
10
40
20
0
20
0
10
10
20
30
% S
% Thr:
0
0
10
0
10
0
10
0
10
0
20
0
0
0
0
% T
% Val:
0
0
10
50
10
10
0
10
10
10
0
10
0
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _