KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2CD3
All Species:
5.76
Human Site:
S608
Identified Species:
14.07
UniProt:
Q4AC94
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4AC94
NP_056346.3
2353
260349
S608
T
E
V
V
R
L
A
S
S
K
I
T
D
G
K
Chimpanzee
Pan troglodytes
XP_001174891
2353
260095
S608
T
E
V
V
R
L
A
S
S
K
I
T
D
G
K
Rhesus Macaque
Macaca mulatta
XP_001115612
2242
248481
M587
F
G
P
L
K
V
T
M
E
L
V
T
D
N
K
Dog
Lupus familis
XP_534012
2030
226571
A375
Q
P
Q
I
R
T
V
A
K
S
H
S
D
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q52KB6
2323
255255
F607
V
V
K
F
Q
Q
R
F
V
C
P
V
E
F
G
Rat
Rattus norvegicus
XP_001066026
2319
255216
W608
G
G
A
M
I
E
H
W
W
S
S
N
L
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519708
2304
248741
D606
F
V
F
P
V
H
F
D
G
A
M
I
E
H
W
Chicken
Gallus gallus
XP_417250
1898
210092
L243
K
D
L
L
S
A
L
L
D
Q
G
N
K
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337534
2147
238438
P492
Y
E
S
V
Q
Q
V
P
S
E
I
T
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781752
2326
256604
S629
V
A
S
I
P
L
R
S
L
I
Q
S
P
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.3
70.9
N.A.
75.8
75.1
N.A.
50.7
46.5
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
99.3
92.8
75.8
N.A.
84.6
83.6
N.A.
64.6
59.4
N.A.
56
N.A.
N.A.
N.A.
N.A.
45.1
P-Site Identity:
100
100
20
13.3
N.A.
0
0
N.A.
0
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
46.6
33.3
N.A.
13.3
6.6
N.A.
13.3
33.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
20
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
0
0
10
10
0
0
0
40
10
0
% D
% Glu:
0
30
0
0
0
10
0
0
10
10
0
0
20
0
0
% E
% Phe:
20
0
10
10
0
0
10
10
0
0
0
0
0
10
10
% F
% Gly:
10
20
0
0
0
0
0
0
10
0
10
0
0
20
10
% G
% His:
0
0
0
0
0
10
10
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
20
10
0
0
0
0
10
30
10
0
0
0
% I
% Lys:
10
0
10
0
10
0
0
0
10
20
0
0
20
0
30
% K
% Leu:
0
0
10
20
0
30
10
10
10
10
0
0
10
10
10
% L
% Met:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
20
0
10
0
% N
% Pro:
0
10
10
10
10
0
0
10
0
0
10
0
10
0
0
% P
% Gln:
10
0
10
0
20
20
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
30
0
20
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
20
0
10
0
0
30
30
20
10
20
0
10
0
% S
% Thr:
20
0
0
0
0
10
10
0
0
0
0
40
0
10
0
% T
% Val:
20
20
20
30
10
10
20
0
10
0
10
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _