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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV420H1 All Species: 16.06
Human Site: S566 Identified Species: 32.12
UniProt: Q4FZB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4FZB7 NP_057112.3 885 99187 S566 N T L N G Y K S S V T E P C P
Chimpanzee Pan troglodytes XP_001173516 885 99214 S566 N T L D G Y K S S V T E P C P
Rhesus Macaque Macaca mulatta XP_001103268 885 99191 S566 N T L D G Y K S S V T E P C P
Dog Lupus familis XP_851524 885 98359 S566 N T L D G Y T S S V T E P C P
Cat Felis silvestris
Mouse Mus musculus Q3U8K7 883 98562 N567 S P L D G Y K N G I L E P C P
Rat Rattus norvegicus P0C2N5 883 98649 N566 S P L D G Y K N G I L E P Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422910 1115 126312 N800 N T L D S Y K N N L T R T R S
Frog Xenopus laevis Q6GP17 855 97576 S539 N S V D G Y R S S H G T V L Q
Zebra Danio Brachydanio rerio Q5U3H2 808 90420 A504 S T R T S L G A Q G A E G T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5E0 1300 137506 E720 K M F S L A E E P Q P E K S E
Honey Bee Apis mellifera XP_395375 977 111827 E636 S R T D P C K E N K N F S R M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800216 932 103465 H579 E T K A F S S H S I D V P T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 90.7 N.A. 87.2 87.3 N.A. N.A. 57.8 70.9 55.1 N.A. 25.1 28.3 N.A. 32
Protein Similarity: 100 99.6 99.6 94 N.A. 93.2 92.7 N.A. N.A. 66.5 80.5 66.7 N.A. 38 46.6 N.A. 49
P-Site Identity: 100 93.3 93.3 86.6 N.A. 53.3 46.6 N.A. N.A. 40 33.3 13.3 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 80 73.3 N.A. N.A. 66.6 60 26.6 N.A. 20 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 9 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 42 0 % C
% Asp: 0 0 0 67 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 9 17 0 0 0 67 0 0 17 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 59 0 9 0 17 9 9 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % I
% Lys: 9 0 9 0 0 0 59 0 0 9 0 0 9 0 0 % K
% Leu: 0 0 59 0 9 9 0 0 0 9 17 0 0 9 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 50 0 0 9 0 0 0 25 17 0 9 0 0 0 0 % N
% Pro: 0 17 0 0 9 0 0 0 9 0 9 0 59 0 50 % P
% Gln: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % Q
% Arg: 0 9 9 0 0 0 9 0 0 0 0 9 0 17 0 % R
% Ser: 34 9 0 9 17 9 9 42 50 0 0 0 9 9 9 % S
% Thr: 0 59 9 9 0 0 9 0 0 0 42 9 9 17 0 % T
% Val: 0 0 9 0 0 0 0 0 0 34 0 9 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 67 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _