Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV420H1 All Species: 11.52
Human Site: S614 Identified Species: 23.03
UniProt: Q4FZB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4FZB7 NP_057112.3 885 99187 S614 T G M S K K K S R Q G K L V K
Chimpanzee Pan troglodytes XP_001173516 885 99214 S614 T G M S K K K S R Q G K L V K
Rhesus Macaque Macaca mulatta XP_001103268 885 99191 S614 T G M S K K K S R Q G K L V K
Dog Lupus familis XP_851524 885 98359 Q614 L S K K K S R Q G K L V K Q V
Cat Felis silvestris
Mouse Mus musculus Q3U8K7 883 98562 K612 N D S C L S R K K F R Q V K P
Rat Rattus norvegicus P0C2N5 883 98649 K612 D S C P S R K K F R Q G K P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422910 1115 126312 K845 D A G T S K K K S R Q G K L V
Frog Xenopus laevis Q6GP17 855 97576 R586 N T S T R N S R Q N R Y I K Q
Zebra Danio Brachydanio rerio Q5U3H2 808 90420 C548 T P S L D S S C P K K G T C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5E0 1300 137506 P806 L S V K S R K P A P S E A S S
Honey Bee Apis mellifera XP_395375 977 111827 S683 T T L R S H K S R R K L L N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800216 932 103465 D625 D D I F I V V D D D D D D T D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 90.7 N.A. 87.2 87.3 N.A. N.A. 57.8 70.9 55.1 N.A. 25.1 28.3 N.A. 32
Protein Similarity: 100 99.6 99.6 94 N.A. 93.2 92.7 N.A. N.A. 66.5 80.5 66.7 N.A. 38 46.6 N.A. 49
P-Site Identity: 100 100 100 6.6 N.A. 0 6.6 N.A. N.A. 13.3 0 6.6 N.A. 6.6 33.3 N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 26.6 20 N.A. N.A. 33.3 33.3 13.3 N.A. 26.6 53.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 9 0 0 0 9 0 0 % A
% Cys: 0 0 9 9 0 0 0 9 0 0 0 0 0 9 0 % C
% Asp: 25 17 0 0 9 0 0 9 9 9 9 9 9 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % E
% Phe: 0 0 0 9 0 0 0 0 9 9 0 0 0 0 0 % F
% Gly: 0 25 9 0 0 0 0 0 9 0 25 25 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 9 17 34 34 59 25 9 17 17 25 25 17 25 % K
% Leu: 17 0 9 9 9 0 0 0 0 0 9 9 34 9 0 % L
% Met: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 9 0 0 0 9 0 0 0 9 0 % N
% Pro: 0 9 0 9 0 0 0 9 9 9 0 0 0 9 17 % P
% Gln: 0 0 0 0 0 0 0 9 9 25 17 9 0 9 9 % Q
% Arg: 0 0 0 9 9 17 17 9 34 25 17 0 0 0 0 % R
% Ser: 0 25 25 25 34 25 17 34 9 0 9 0 0 9 9 % S
% Thr: 42 17 0 17 0 0 0 0 0 0 0 0 9 9 0 % T
% Val: 0 0 9 0 0 9 9 0 0 0 0 9 9 25 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _