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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM188B
All Species:
13.33
Human Site:
S435
Identified Species:
32.59
UniProt:
Q4G0A6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G0A6
NP_115598.2
757
84402
S435
N
E
E
W
K
L
Q
S
F
S
F
S
N
T
A
Chimpanzee
Pan troglodytes
XP_527714
757
84304
S435
N
E
E
W
K
L
Q
S
F
S
F
S
N
T
A
Rhesus Macaque
Macaca mulatta
XP_001084657
753
83692
S431
N
E
E
W
K
L
Q
S
F
S
F
S
N
T
A
Dog
Lupus familis
XP_532503
1064
115963
S613
N
E
E
W
K
L
Q
S
F
S
F
S
D
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQI9
744
82918
N422
S
E
E
W
K
L
Q
N
F
S
F
N
D
I
A
Rat
Rattus norvegicus
XP_001058587
756
84471
N434
S
E
E
W
K
L
Q
N
F
S
F
N
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510974
534
57952
Q239
C
G
V
L
A
A
V
Q
A
C
V
L
Q
K
L
Chicken
Gallus gallus
XP_418488
261
29438
Frog
Xenopus laevis
NP_001089772
361
40200
P66
E
N
K
S
R
E
K
P
L
K
T
L
L
E
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198370
699
76458
D404
K
E
V
S
T
L
G
D
L
E
M
G
D
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
88.6
56.9
N.A.
72.7
74.6
N.A.
42.6
26.5
21.3
N.A.
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
99
92
61.8
N.A.
82.3
84.6
N.A.
52.5
31.1
35
N.A.
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
100
86.6
N.A.
66.6
66.6
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
60
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
40
0
10
% D
% Glu:
10
70
60
0
0
10
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
60
0
60
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% I
% Lys:
10
0
10
0
60
0
10
0
0
10
0
0
0
20
0
% K
% Leu:
0
0
0
10
0
70
0
0
20
0
0
20
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
40
10
0
0
0
0
0
20
0
0
0
20
30
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
60
10
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
20
0
0
0
40
0
60
0
40
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
0
30
0
% T
% Val:
0
0
20
0
0
0
10
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _