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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C5orf33
All Species:
33.33
Human Site:
S376
Identified Species:
61.11
UniProt:
Q4G0N4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G0N4
NP_001078880.1
442
49433
S376
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Chimpanzee
Pan troglodytes
XP_517804
464
51945
S398
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Rhesus Macaque
Macaca mulatta
XP_001092624
464
51916
S398
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Dog
Lupus familis
XP_855394
464
52080
S398
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5H8
452
50840
S386
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Rat
Rattus norvegicus
Q1HCL7
425
48098
S359
E
E
P
K
I
L
F
S
I
R
E
P
I
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511837
342
38763
I277
E
P
K
M
L
F
S
I
R
E
P
I
A
N
R
Chicken
Gallus gallus
XP_425010
355
40050
I290
E
P
K
M
F
F
S
I
R
E
P
I
V
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003465
281
31662
S216
E
E
D
K
L
F
F
S
V
R
E
P
I
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788288
413
46815
E348
R
L
C
Y
S
I
R
E
Q
I
C
V
G
V
W
Honey Bee
Apis mellifera
XP_392182
409
47245
D344
K
L
C
Y
V
I
R
D
M
I
V
N
D
L
W
Nematode Worm
Caenorhab. elegans
NP_496565
431
48622
S366
D
R
K
Q
L
A
F
S
V
R
D
P
I
F
N
Sea Urchin
Strong. purpuratus
XP_795192
365
41578
T300
A
D
P
R
M
A
Y
T
V
R
D
P
V
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
94.8
92
N.A.
90.7
86.8
N.A.
70.3
68.3
N.A.
46.8
N.A.
33.9
34.3
42.5
42
Protein Similarity:
100
95
94.8
92.8
N.A.
92.9
89.8
N.A.
74.6
74.6
N.A.
54
N.A.
54.9
54.2
61
58.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
66.6
N.A.
0
0
40
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
13.3
N.A.
80
N.A.
6.6
26.6
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
0
0
0
0
0
8
47
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
0
8
0
0
16
0
8
0
0
% D
% Glu:
70
54
0
0
0
0
0
8
0
16
54
0
0
0
0
% E
% Phe:
0
0
0
0
8
24
62
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
47
16
0
16
47
16
0
16
62
0
0
% I
% Lys:
8
0
24
54
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
0
0
24
47
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
16
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
70
% N
% Pro:
0
16
54
0
0
0
0
0
0
0
16
70
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
0
8
0
0
16
0
16
70
0
0
0
0
16
% R
% Ser:
0
0
0
0
8
0
16
62
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
24
0
8
8
16
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% W
% Tyr:
0
0
0
16
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _