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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP27C1
All Species:
9.7
Human Site:
S152
Identified Species:
23.7
UniProt:
Q4G0S4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G0S4
NP_001001665.3
372
42632
S152
M
D
R
G
R
R
V
S
G
G
L
L
T
Y
L
Chimpanzee
Pan troglodytes
XP_525906
776
87788
S556
M
D
R
G
R
R
V
S
G
G
L
L
T
Y
L
Rhesus Macaque
Macaca mulatta
XP_001103470
811
88801
S591
T
D
R
G
R
R
A
S
G
G
L
L
T
Y
L
Dog
Lupus familis
XP_540989
490
55880
R270
M
D
R
G
E
R
V
R
G
G
L
L
T
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG1
533
60702
V309
T
G
P
D
G
V
R
V
S
G
Y
L
H
F
L
Rat
Rattus norvegicus
P17178
533
60715
V309
A
G
P
D
G
V
Q
V
S
G
Y
L
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422077
536
61257
N316
L
D
Q
G
E
E
V
N
G
G
L
L
T
Y
L
Frog
Xenopus laevis
NP_001087801
476
54668
Q256
L
N
K
G
E
E
V
Q
G
G
V
L
T
H
L
Zebra Danio
Brachydanio rerio
NP_001106808
468
53644
K249
M
E
K
S
E
E
I
K
G
G
L
L
T
H
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR9
524
60579
S295
R
K
S
S
Q
G
D
S
N
D
H
K
S
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
45.2
68.3
N.A.
29.2
29.4
N.A.
N.A.
55.7
55.8
54.9
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
47.8
45.3
72.2
N.A.
46.9
47.2
N.A.
N.A.
63.4
69.1
67.5
N.A.
42.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
20
20
N.A.
N.A.
66.6
46.6
40
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
80
N.A.
26.6
26.6
N.A.
N.A.
86.6
80
73.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
50
0
20
0
0
10
0
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
0
40
30
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
0
20
0
60
20
10
0
0
70
90
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
20
20
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
20
0
0
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
20
0
0
0
0
0
0
0
0
0
60
90
0
0
90
% L
% Met:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
40
0
30
40
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
20
0
0
0
40
20
0
0
0
10
0
0
% S
% Thr:
20
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% T
% Val:
0
0
0
0
0
20
50
20
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
20
0
0
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _