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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 12.42
Human Site: S412 Identified Species: 45.56
UniProt: Q4G0U5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4G0U5 NP_001025167.1 554 64234 S412 T K E S R H G S S I P V T Q K
Chimpanzee Pan troglodytes XP_515762 684 78881 S542 T K E S R H G S S I P V T Q K
Rhesus Macaque Macaca mulatta XP_001084153 554 64061 S412 T K E S H H G S S I P V T Q K
Dog Lupus familis XP_533321 875 98723 L707 G T R L R D A L T L S R D A Q
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422119 644 74304 S495 T K E C P K G S S I P I T Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002660420 829 93536 G688 I T S A N V R G V D N T T K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792585 708 79379 G547 S D P K N K H G A T L K R Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 95.8 41.7 N.A. N.A. N.A. N.A. N.A. 37.8 N.A. 22 N.A. N.A. N.A. N.A. 25.4
Protein Similarity: 100 80.8 98 50.8 N.A. N.A. N.A. N.A. N.A. 54.1 N.A. 37.3 N.A. N.A. N.A. N.A. 43.6
P-Site Identity: 100 100 93.3 6.6 N.A. N.A. N.A. N.A. N.A. 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 26.6 N.A. N.A. N.A. N.A. N.A. 80 N.A. 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 0 15 0 15 0 0 0 0 15 0 % A
% Cys: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 15 0 0 0 15 0 0 15 0 0 % D
% Glu: 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 0 58 29 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 15 43 15 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 58 0 15 0 0 0 % I
% Lys: 0 58 0 15 0 29 0 0 0 0 0 15 0 15 72 % K
% Leu: 0 0 0 15 0 0 0 15 0 15 15 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 29 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 0 0 15 0 15 0 0 0 0 0 58 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 58 15 % Q
% Arg: 0 0 15 0 43 0 15 0 0 0 0 15 15 0 0 % R
% Ser: 15 0 15 43 0 0 0 58 58 0 15 0 0 0 0 % S
% Thr: 58 29 0 0 0 0 0 0 15 15 0 15 72 0 0 % T
% Val: 0 0 0 0 0 15 0 0 15 0 0 43 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _