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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCTD21 All Species: 26.97
Human Site: S176 Identified Species: 65.93
UniProt: Q4G0X4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4G0X4 NP_001025030.1 260 29643 S176 G N L S S I T S H L Q D P N H
Chimpanzee Pan troglodytes XP_523831 232 25841 H154 D R A E G S P H F H L E W A P
Rhesus Macaque Macaca mulatta XP_001093230 260 29621 S176 G N L S S I T S H L Q D P N H
Dog Lupus familis XP_851103 260 29610 S176 G N L S S I T S H L Q D P N H
Cat Felis silvestris
Mouse Mus musculus NP_001034128 260 29639 S176 G N L S S I T S H L Q D P N H
Rat Rattus norvegicus NP_001102621 260 29605 S176 G N L S S I T S H L Q D P N H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519321 396 44413 S176 G N L S S I S S Q L Q D P N H
Chicken Gallus gallus XP_425657 260 29738 S176 G N L S S I S S Y L Q D P N H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074463 237 27671 F160 L E G I S N N F T R W N K H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190874 218 25162 V141 I Y G S S E T V Q K I P V F M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.7 99.2 99.6 N.A. 99.6 98.4 N.A. 58.3 91.1 N.A. 37.3 N.A. N.A. N.A. N.A. 34.6
Protein Similarity: 100 51.1 99.6 100 N.A. 99.6 98.8 N.A. 63.8 98 N.A. 53.4 N.A. N.A. N.A. N.A. 50.7
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 86.6 86.6 N.A. 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 100 N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % D
% Glu: 0 10 0 10 0 10 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % F
% Gly: 70 0 20 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 50 10 0 0 0 10 70 % H
% Ile: 10 0 0 10 0 70 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % K
% Leu: 10 0 70 0 0 0 0 0 0 70 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 0 70 0 0 0 10 10 0 0 0 0 10 0 70 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 10 70 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 20 0 70 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 80 90 10 20 70 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 60 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _