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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO43
All Species:
6.06
Human Site:
S381
Identified Species:
14.81
UniProt:
Q4G163
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G163
NP_001025031.2
708
78402
S381
K
T
R
H
L
G
R
S
R
R
L
S
T
L
R
Chimpanzee
Pan troglodytes
XP_519884
708
78455
S381
K
T
R
H
L
G
R
S
R
R
L
S
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001096807
674
74331
R376
V
H
P
D
S
E
K
R
A
A
A
A
S
A
I
Dog
Lupus familis
XP_539103
666
74213
S368
E
T
E
K
D
S
D
S
E
A
T
P
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDI2
640
71153
H342
E
D
E
M
Q
T
V
H
P
N
S
D
S
G
V
Rat
Rattus norvegicus
Q66H04
664
73210
V365
H
P
S
A
G
V
R
V
G
T
A
S
G
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518783
536
59440
S238
S
R
N
I
C
R
E
S
T
P
D
D
P
H
E
Chicken
Gallus gallus
XP_418357
667
74473
G369
S
E
T
E
D
H
H
G
S
P
N
S
A
H
T
Frog
Xenopus laevis
Q8AXF4
651
72285
V353
V
E
E
E
G
N
E
V
P
V
L
S
S
A
Y
Zebra Danio
Brachydanio rerio
Q0V967
384
43025
S86
D
E
V
I
F
S
G
S
G
L
T
E
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.3
75.2
N.A.
62.7
62.1
N.A.
40.5
44
43.2
21.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
93.7
83
N.A.
73.3
73.4
N.A.
52.1
60.1
60.1
34.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
0
13.3
N.A.
6.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
13.3
20
N.A.
6.6
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
20
20
10
10
30
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
20
0
10
0
0
0
10
20
10
0
0
% D
% Glu:
20
30
30
20
0
10
20
0
10
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
20
20
10
10
20
0
0
0
10
10
10
% G
% His:
10
10
0
20
0
10
10
10
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
20
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
20
0
0
0
0
10
30
0
0
20
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
20
20
0
10
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
20
0
0
10
30
10
20
20
0
0
0
0
20
% R
% Ser:
20
0
10
0
10
20
0
50
10
0
10
50
30
10
0
% S
% Thr:
0
30
10
0
0
10
0
0
10
10
20
0
20
0
10
% T
% Val:
20
0
10
0
0
10
10
20
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _