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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO43 All Species: 4.55
Human Site: S418 Identified Species: 11.11
UniProt: Q4G163 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4G163 NP_001025031.2 708 78402 S418 A A A A S A I S E G Q L S S D
Chimpanzee Pan troglodytes XP_519884 708 78455 S418 A A A A S A I S E G Q L S S D
Rhesus Macaque Macaca mulatta XP_001096807 674 74331 H413 T P A L Q L V H E L F M K S K
Dog Lupus familis XP_539103 666 74213 H405 T P A L Q L V H E L F M R S K
Cat Felis silvestris
Mouse Mus musculus Q8CDI2 640 71153 V379 N T P A L Q L V Q E L F M K S
Rat Rattus norvegicus Q66H04 664 73210 C402 T P A L Q L V C E L F M K S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518783 536 59440 N275 R G T Q S K T N E D T F V T P
Chicken Gallus gallus XP_418357 667 74473 D406 D S T V N Y G D L S R T P A L
Frog Xenopus laevis Q8AXF4 651 72285 D390 H S L L S S D D L T G K P A L
Zebra Danio Brachydanio rerio Q0V967 384 43025 L123 N C V S S Q S L D V E C H S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 92.3 75.2 N.A. 62.7 62.1 N.A. 40.5 44 43.2 21.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 93.7 83 N.A. 73.3 73.4 N.A. 52.1 60.1 60.1 34.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 20 N.A. 6.6 20 N.A. 13.3 0 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 33.3 N.A. 20 33.3 N.A. 26.6 26.6 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 20 50 30 0 20 0 0 0 0 0 0 0 20 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 0 0 0 10 20 10 10 0 0 0 0 20 % D
% Glu: 0 0 0 0 0 0 0 0 60 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 30 20 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 20 10 0 0 0 10 % G
% His: 10 0 0 0 0 0 0 20 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 10 20 10 30 % K
% Leu: 0 0 10 40 10 30 10 10 20 30 10 20 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 30 10 0 0 % M
% Asn: 20 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 30 10 0 0 0 0 0 0 0 0 0 20 0 10 % P
% Gln: 0 0 0 10 30 20 0 0 10 0 20 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % R
% Ser: 0 20 0 10 50 10 10 20 0 10 0 0 20 60 10 % S
% Thr: 30 10 20 0 0 0 10 0 0 10 10 10 0 10 0 % T
% Val: 0 0 10 10 0 0 30 10 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _