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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSF3
All Species:
18.18
Human Site:
S281
Identified Species:
40
UniProt:
Q4G176
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G176
NP_777577.2
576
64114
S281
Q
V
W
E
K
F
L
S
S
E
T
P
R
I
N
Chimpanzee
Pan troglodytes
XP_511166
705
76830
S281
Q
V
W
E
K
F
L
S
S
E
T
P
R
I
N
Rhesus Macaque
Macaca mulatta
XP_001101263
1154
124364
V880
A
L
L
C
P
L
W
V
G
A
T
C
V
M
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3URE1
583
65058
S281
Q
V
W
E
K
F
L
S
S
E
A
P
Q
I
T
Rat
Rattus norvegicus
XP_001079424
583
65247
S281
Q
V
W
E
K
F
L
S
S
E
A
P
Q
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511705
582
65537
S287
E
I
W
E
K
F
L
S
S
K
A
P
R
I
N
Chicken
Gallus gallus
XP_425134
471
52458
S197
V
E
D
V
P
L
A
S
S
A
S
W
K
D
R
Frog
Xenopus laevis
Q6GLK6
578
64539
G284
T
V
W
Q
H
F
L
G
R
D
V
P
S
I
N
Zebra Danio
Brachydanio rerio
XP_690782
579
64214
Q281
M
L
P
D
F
S
A
Q
K
V
W
E
Q
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785115
560
63035
A263
V
M
L
P
D
F
D
A
E
K
V
W
H
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P21
546
59356
G252
G
L
A
A
F
A
T
G
L
L
A
Y
G
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
36.6
N.A.
N.A.
78
79.2
N.A.
66.1
53.1
60.2
59.9
N.A.
N.A.
N.A.
N.A.
49.3
Protein Similarity:
100
73.3
39.4
N.A.
N.A.
87.3
88.3
N.A.
80.4
63.3
76.6
75.3
N.A.
N.A.
N.A.
N.A.
68
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
86.6
N.A.
73.3
13.3
46.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
86.6
93.3
N.A.
93.3
26.6
60
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
10
19
10
0
19
37
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
10
10
0
10
0
0
10
0
0
0
10
0
% D
% Glu:
10
10
0
46
0
0
0
0
10
37
0
10
0
0
0
% E
% Phe:
0
0
0
0
19
64
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
19
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
55
10
% I
% Lys:
0
0
0
0
46
0
0
0
10
19
0
0
10
0
0
% K
% Leu:
0
28
19
0
0
19
55
0
10
10
0
0
0
10
10
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
19
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% N
% Pro:
0
0
10
10
19
0
0
0
0
0
0
55
0
0
0
% P
% Gln:
37
0
0
10
0
0
0
10
0
0
0
0
28
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
28
0
10
% R
% Ser:
0
0
0
0
0
10
0
55
55
0
10
0
10
10
0
% S
% Thr:
10
0
0
0
0
0
10
0
0
0
28
0
0
0
19
% T
% Val:
19
46
0
10
0
0
0
10
0
10
19
0
10
0
0
% V
% Trp:
0
0
55
0
0
0
10
0
0
0
10
19
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _