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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSF3
All Species:
9.7
Human Site:
S29
Identified Species:
21.33
UniProt:
Q4G176
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G176
NP_777577.2
576
64114
S29
A
P
A
R
H
R
G
S
G
L
L
H
T
A
P
Chimpanzee
Pan troglodytes
XP_511166
705
76830
S29
A
P
A
R
H
R
G
S
G
L
L
H
T
A
P
Rhesus Macaque
Macaca mulatta
XP_001101263
1154
124364
S649
A
P
V
R
H
R
R
S
G
L
L
H
T
A
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3URE1
583
65058
H29
I
P
R
R
H
R
G
H
S
L
L
P
T
T
P
Rat
Rattus norvegicus
XP_001079424
583
65247
H29
T
A
R
R
H
R
G
H
S
L
L
H
T
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511705
582
65537
G35
L
R
R
V
Y
R
V
G
R
L
L
H
T
A
G
Chicken
Gallus gallus
XP_425134
471
52458
Frog
Xenopus laevis
Q6GLK6
578
64539
S30
R
R
R
T
P
Q
H
S
C
S
F
H
I
S
K
Zebra Danio
Brachydanio rerio
XP_690782
579
64214
F38
G
N
V
Q
H
R
T
F
T
F
S
D
L
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785115
560
63035
R30
G
L
S
L
L
P
R
R
Y
S
S
A
G
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P21
546
59356
N29
T
P
I
P
L
P
P
N
P
S
L
D
V
T
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
36.6
N.A.
N.A.
78
79.2
N.A.
66.1
53.1
60.2
59.9
N.A.
N.A.
N.A.
N.A.
49.3
Protein Similarity:
100
73.3
39.4
N.A.
N.A.
87.3
88.3
N.A.
80.4
63.3
76.6
75.3
N.A.
N.A.
N.A.
N.A.
68
P-Site Identity:
100
100
86.6
N.A.
N.A.
60
66.6
N.A.
40
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
N.A.
N.A.
60
66.6
N.A.
46.6
0
26.6
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
19
0
0
0
0
0
0
0
0
10
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% F
% Gly:
19
0
0
0
0
0
37
10
28
0
0
0
10
0
10
% G
% His:
0
0
0
0
55
0
10
19
0
0
0
55
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
0
10
19
0
0
0
0
55
64
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
46
0
10
10
19
10
0
10
0
0
10
0
0
46
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
19
37
46
0
64
19
10
10
0
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
0
37
19
28
19
0
0
10
10
% S
% Thr:
19
0
0
10
0
0
10
0
10
0
0
0
55
19
10
% T
% Val:
0
0
19
10
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _