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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSF3
All Species:
29.39
Human Site:
S75
Identified Species:
64.67
UniProt:
Q4G176
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G176
NP_777577.2
576
64114
S75
Y
R
E
L
Y
S
R
S
L
R
L
S
Q
E
I
Chimpanzee
Pan troglodytes
XP_511166
705
76830
S75
Y
R
E
L
Y
S
R
S
L
R
L
S
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001101263
1154
124364
S695
Y
R
E
L
Y
S
R
S
L
R
L
S
Q
E
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3URE1
583
65058
S75
Y
R
E
L
Y
D
R
S
L
C
L
A
Q
E
I
Rat
Rattus norvegicus
XP_001079424
583
65247
S75
Y
R
E
L
Y
D
R
S
L
C
L
A
Q
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511705
582
65537
S81
Y
K
D
L
Y
F
K
S
L
R
L
S
Q
H
I
Chicken
Gallus gallus
XP_425134
471
52458
L21
A
R
C
L
L
R
D
L
H
R
W
G
L
R
R
Frog
Xenopus laevis
Q6GLK6
578
64539
S76
Y
K
D
L
Y
I
R
S
Q
A
L
S
K
M
I
Zebra Danio
Brachydanio rerio
XP_690782
579
64214
S84
Y
H
S
L
Y
K
N
S
K
I
L
A
G
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785115
560
63035
S72
Y
N
D
I
I
S
W
S
M
V
L
S
R
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P21
546
59356
A71
W
R
A
V
E
S
V
A
D
C
L
S
E
I
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
36.6
N.A.
N.A.
78
79.2
N.A.
66.1
53.1
60.2
59.9
N.A.
N.A.
N.A.
N.A.
49.3
Protein Similarity:
100
73.3
39.4
N.A.
N.A.
87.3
88.3
N.A.
80.4
63.3
76.6
75.3
N.A.
N.A.
N.A.
N.A.
68
P-Site Identity:
100
100
100
N.A.
N.A.
80
80
N.A.
66.6
20
53.3
40
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
20
73.3
46.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
10
0
10
0
28
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
28
0
0
0
0
0
% C
% Asp:
0
0
28
0
0
19
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
46
0
10
0
0
0
0
0
0
0
10
46
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
28
0
% H
% Ile:
0
0
0
10
10
10
0
0
0
10
0
0
0
10
82
% I
% Lys:
0
19
0
0
0
10
10
0
10
0
0
0
10
0
0
% K
% Leu:
0
0
0
82
10
0
0
10
55
0
91
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
55
0
0
% Q
% Arg:
0
64
0
0
0
10
55
0
0
46
0
0
10
10
10
% R
% Ser:
0
0
10
0
0
46
0
82
0
0
0
64
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% W
% Tyr:
82
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _