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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSF3
All Species:
10.91
Human Site:
Y355
Identified Species:
24
UniProt:
Q4G176
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4G176
NP_777577.2
576
64114
Y355
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
M
Chimpanzee
Pan troglodytes
XP_511166
705
76830
Y355
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
M
Rhesus Macaque
Macaca mulatta
XP_001101263
1154
124364
P948
G
Q
V
G
S
V
L
P
S
K
E
C
V
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3URE1
583
65058
R354
T
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
Rat
Rattus norvegicus
XP_001079424
583
65247
E353
A
T
G
H
T
L
L
E
R
Y
G
M
T
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511705
582
65537
Y361
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
M
Chicken
Gallus gallus
XP_425134
471
52458
C265
G
V
I
N
K
L
L
C
P
L
W
V
G
A
T
Frog
Xenopus laevis
Q6GLK6
578
64539
R357
T
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
Zebra Danio
Brachydanio rerio
XP_690782
579
64214
T355
L
E
R
W
A
E
I
T
D
H
V
L
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785115
560
63035
T338
M
D
E
W
E
Q
T
T
G
H
R
L
L
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P21
546
59356
S320
L
C
G
G
A
P
L
S
K
E
V
T
E
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
36.6
N.A.
N.A.
78
79.2
N.A.
66.1
53.1
60.2
59.9
N.A.
N.A.
N.A.
N.A.
49.3
Protein Similarity:
100
73.3
39.4
N.A.
N.A.
87.3
88.3
N.A.
80.4
63.3
76.6
75.3
N.A.
N.A.
N.A.
N.A.
68
P-Site Identity:
100
100
6.6
N.A.
N.A.
6.6
0
N.A.
100
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
6.6
6.6
N.A.
100
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
10
37
19
10
0
10
10
28
28
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
46
19
19
19
0
0
0
0
37
19
10
0
10
37
19
% G
% His:
0
28
19
10
0
0
0
0
0
19
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
28
19
10
% I
% Lys:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% K
% Leu:
19
0
0
28
46
37
37
0
0
10
0
19
19
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
28
19
10
0
0
28
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
28
19
10
0
10
0
0
0
19
% R
% Ser:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% S
% Thr:
19
10
28
19
10
0
10
19
0
0
28
28
10
10
10
% T
% Val:
0
10
10
0
0
10
0
0
0
0
19
10
10
0
0
% V
% Trp:
0
0
0
19
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
19
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _