KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
15.76
Human Site:
S716
Identified Species:
31.52
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
S716
E
L
G
L
D
S
T
S
V
F
E
D
L
K
K
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
S716
E
L
G
L
D
S
T
S
V
F
E
D
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
S716
E
L
G
L
D
S
T
S
V
F
E
D
L
K
K
Dog
Lupus familis
XP_531803
727
83861
S716
E
L
G
L
D
S
T
S
I
F
E
N
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
D714
E
L
G
L
D
S
T
D
A
F
E
A
L
K
K
Rat
Rattus norvegicus
Q5HZA6
726
83463
D715
E
L
G
L
D
S
T
D
A
F
E
A
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
L332
L
A
F
L
Y
Q
E
L
G
L
R
P
P
P
P
Chicken
Gallus gallus
Q5ZKL5
732
84295
R721
D
S
L
N
E
V
A
R
H
L
A
F
L
K
K
Frog
Xenopus laevis
Q32N48
707
80150
L696
F
L
H
M
E
L
K
L
D
I
P
R
R
C
K
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
S681
L
Y
T
E
L
G
L
S
L
D
Q
Q
R
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
T708
R
S
G
R
A
Y
G
T
M
H
H
Q
K
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
L772
T
A
F
E
Y
A
F
L
M
K
A
L
G
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
6.6
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
9
9
0
17
0
17
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
50
0
0
17
9
9
0
25
0
0
9
% D
% Glu:
50
0
0
17
17
0
9
0
0
0
50
0
0
0
0
% E
% Phe:
9
0
17
0
0
0
9
0
0
50
0
9
0
0
0
% F
% Gly:
0
0
59
0
0
9
9
0
9
0
0
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
9
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
9
0
0
9
59
67
% K
% Leu:
17
59
9
59
9
9
9
25
9
17
0
9
59
9
0
% L
% Met:
0
0
0
9
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
9
9
9
9
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
9
17
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
9
0
0
9
9
17
0
9
% R
% Ser:
0
17
0
0
0
50
0
42
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
0
0
50
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
9
0
0
25
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
17
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _