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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
31.21
Human Site:
T246
Identified Species:
62.42
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
T246
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
T246
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
T246
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Dog
Lupus familis
XP_531803
727
83861
T246
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
T244
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Rat
Rattus norvegicus
Q5HZA6
726
83463
T245
K
R
N
E
R
F
Y
T
E
K
D
P
S
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
Chicken
Gallus gallus
Q5ZKL5
732
84295
T260
K
Y
T
K
L
V
Y
T
E
Q
D
A
R
F
F
Frog
Xenopus laevis
Q32N48
707
80150
T223
G
A
A
Q
L
V
Y
T
E
N
D
P
R
F
F
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
N228
D
Q
R
L
V
T
I
N
C
S
S
K
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
T225
F
F
V
D
L
S
H
T
K
D
R
R
Y
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
T265
E
A
G
F
L
V
F
T
E
K
D
V
N
C
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
40
40
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
60
53.3
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% C
% Asp:
9
0
0
9
0
0
0
0
0
9
75
0
0
0
0
% D
% Glu:
9
0
0
50
0
0
0
0
75
0
0
0
0
0
0
% E
% Phe:
9
9
0
9
0
50
9
0
0
0
0
0
0
17
67
% F
% Gly:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
0
9
0
0
0
0
9
59
0
9
0
0
0
% K
% Leu:
0
0
0
9
34
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
0
0
0
0
9
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
50
9
0
50
0
0
0
0
0
9
9
17
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
9
9
0
50
9
9
% S
% Thr:
0
0
9
0
0
9
0
84
0
0
0
0
9
0
0
% T
% Val:
0
0
9
0
9
25
0
0
0
0
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
67
0
0
0
0
0
9
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _