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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO6
All Species:
20
Human Site:
S256
Identified Species:
44
UniProt:
Q4KMQ2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KMQ2
NP_001020527.2
910
106165
S256
D
C
K
F
R
R
Q
S
E
D
P
S
C
P
N
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
S476
D
C
K
F
R
R
Q
S
E
D
P
S
C
P
N
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
S256
D
C
K
F
R
R
Q
S
E
D
P
S
C
P
N
Dog
Lupus familis
XP_852020
885
103276
L242
S
C
P
S
E
R
Y
L
L
Y
R
E
W
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9J9
911
106237
S257
D
C
R
F
N
Y
E
S
E
D
I
S
C
P
S
Rat
Rattus norvegicus
Q6IFT6
860
97152
S246
P
F
S
V
V
P
E
S
S
Q
V
L
G
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514758
556
64820
Chicken
Gallus gallus
XP_416045
912
106141
S258
D
S
S
F
G
H
L
S
T
D
P
D
C
P
S
Frog
Xenopus laevis
NP_001086810
896
105149
T244
D
C
R
Y
W
K
K
T
D
E
R
S
C
E
R
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Q60
D
Q
L
L
F
P
A
Q
D
G
Q
K
P
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
S274
G
D
Y
K
S
K
H
S
L
L
T
H
G
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
99.2
86.2
N.A.
90.3
36.5
N.A.
51
77.8
53
22.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
80.4
99.7
90.9
N.A.
95
56.3
N.A.
57.2
88.8
69.1
38.1
N.A.
N.A.
N.A.
N.A.
60.2
P-Site Identity:
100
100
100
13.3
N.A.
60
6.6
N.A.
0
46.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
80
13.3
N.A.
0
53.3
73.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
55
0
0
0
0
0
0
0
0
0
0
55
0
0
% C
% Asp:
64
10
0
0
0
0
0
0
19
46
0
10
0
0
0
% D
% Glu:
0
0
0
0
10
0
19
0
37
10
0
10
0
10
0
% E
% Phe:
0
10
0
46
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
10
0
0
19
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
28
10
0
19
10
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
10
10
0
0
10
10
19
10
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
28
% N
% Pro:
10
0
10
0
0
19
0
0
0
0
37
0
10
55
10
% P
% Gln:
0
10
0
0
0
0
28
10
0
10
10
0
0
0
10
% Q
% Arg:
0
0
19
0
28
37
0
0
0
0
19
0
0
0
10
% R
% Ser:
10
10
19
10
10
0
0
64
10
0
0
46
0
0
19
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
10
% T
% Val:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
10
0
10
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _