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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO6 All Species: 22.12
Human Site: T646 Identified Species: 48.67
UniProt: Q4KMQ2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4KMQ2 NP_001020527.2 910 106165 T646 V S G S E K I T P R W E Q D Y
Chimpanzee Pan troglodytes XP_509014 1130 129847 T866 V S G S E K I T P R W E Q D Y
Rhesus Macaque Macaca mulatta XP_001092876 910 106164 T646 V S G S E K I T P R W E Q D Y
Dog Lupus familis XP_852020 885 103276 S621 A S R T E K K S P R W E Q D Y
Cat Felis silvestris
Mouse Mus musculus Q6P9J9 911 106237 T647 V S G S E K I T P R W E Q D Y
Rat Rattus norvegicus Q6IFT6 860 97152 A625 R K K A G M G A N P A P W E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514758 556 64820 V327 I T Q E E E H V P Y T S C G K
Chicken Gallus gallus XP_416045 912 106141 V649 D A R S E K T V P R W E Q D Y
Frog Xenopus laevis NP_001086810 896 105149 Y633 R N H P E N L Y S R W E Q D G
Zebra Danio Brachydanio rerio Q4V8U5 646 74505 Y418 N C F A S L F Y I A F V M Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 Y657 E K S G K G R Y E Q W E Q D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 99.2 86.2 N.A. 90.3 36.5 N.A. 51 77.8 53 22.4 N.A. N.A. N.A. N.A. 40.8
Protein Similarity: 100 80.4 99.7 90.9 N.A. 95 56.3 N.A. 57.2 88.8 69.1 38.1 N.A. N.A. N.A. N.A. 60.2
P-Site Identity: 100 100 100 66.6 N.A. 100 0 N.A. 13.3 66.6 40 0 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 80 N.A. 100 13.3 N.A. 33.3 73.3 53.3 13.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 19 0 0 0 10 0 10 10 0 0 0 19 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 73 10 % D
% Glu: 10 0 0 10 73 10 0 0 10 0 0 73 0 10 0 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 37 10 10 10 10 0 0 0 0 0 0 10 10 % G
% His: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 37 0 10 0 0 0 0 0 0 % I
% Lys: 0 19 10 0 10 55 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % M
% Asn: 10 10 0 0 0 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 64 10 0 10 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 10 0 0 73 10 0 % Q
% Arg: 19 0 19 0 0 0 10 0 0 64 0 0 0 0 0 % R
% Ser: 0 46 10 46 10 0 0 10 10 0 0 10 0 0 0 % S
% Thr: 0 10 0 10 0 0 10 37 0 0 10 0 0 0 0 % T
% Val: 37 0 0 0 0 0 0 19 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 73 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 28 0 10 0 0 0 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _