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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO6
All Species:
21.82
Human Site:
Y422
Identified Species:
48
UniProt:
Q4KMQ2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KMQ2
NP_001020527.2
910
106165
Y422
E
E
Q
A
R
P
E
Y
E
A
R
C
T
H
V
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
Y642
E
E
Q
A
R
P
E
Y
E
A
R
C
T
H
V
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
Y422
E
E
Q
A
R
P
E
Y
E
A
R
C
T
H
V
Dog
Lupus familis
XP_852020
885
103276
Y397
E
E
Q
P
R
P
E
Y
E
A
Q
C
T
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9J9
911
106237
Y423
E
E
Q
A
R
P
E
Y
E
A
Q
C
N
H
V
Rat
Rattus norvegicus
Q6IFT6
860
97152
D401
W
D
C
S
D
Y
E
D
I
E
E
R
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514758
556
64820
D119
N
V
K
K
F
G
I
D
R
L
V
N
S
G
I
Chicken
Gallus gallus
XP_416045
912
106141
Y425
E
E
Q
I
R
P
E
Y
E
A
Q
C
T
H
V
Frog
Xenopus laevis
NP_001086810
896
105149
P409
Q
Q
Q
L
Q
L
R
P
E
Y
E
A
K
C
T
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
L210
Y
F
G
E
G
L
G
L
Y
F
G
F
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
E430
W
D
L
F
G
F
E
E
Q
E
E
N
I
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
99.2
86.2
N.A.
90.3
36.5
N.A.
51
77.8
53
22.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
80.4
99.7
90.9
N.A.
95
56.3
N.A.
57.2
88.8
69.1
38.1
N.A.
N.A.
N.A.
N.A.
60.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
0
86.6
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
20
93.3
33.3
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
37
0
0
0
0
0
55
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
55
0
10
0
% C
% Asp:
0
19
0
0
10
0
0
19
0
0
0
0
0
0
0
% D
% Glu:
55
55
0
10
0
0
73
10
64
19
28
0
0
10
0
% E
% Phe:
0
10
0
10
10
10
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
0
10
0
19
10
10
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% H
% Ile:
0
0
0
10
0
0
10
0
10
0
0
0
10
0
10
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
10
10
0
19
0
10
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
19
10
0
0
% N
% Pro:
0
0
0
10
0
55
0
10
0
0
0
0
10
0
19
% P
% Gln:
10
10
64
0
10
0
0
0
10
0
28
0
0
0
0
% Q
% Arg:
0
0
0
0
55
0
10
0
10
0
28
10
0
19
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
55
% V
% Trp:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
55
10
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _