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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO6 All Species: 22.73
Human Site: Y770 Identified Species: 50
UniProt: Q4KMQ2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4KMQ2 NP_001020527.2 910 106165 Y770 P Y G D H T S Y T M E G Y I N
Chimpanzee Pan troglodytes XP_509014 1130 129847 Y990 P Y G D H T S Y T M E G Y I N
Rhesus Macaque Macaca mulatta XP_001092876 910 106164 Y770 P Y G D H T S Y T M E G Y I N
Dog Lupus familis XP_852020 885 103276 Y745 P Y G N H T Q Y T M E G Y I N
Cat Felis silvestris
Mouse Mus musculus Q6P9J9 911 106237 Y771 P Y G D H T Y Y T M D G Y I N
Rat Rattus norvegicus Q6IFT6 860 97152 D727 F L L A F S S D F L P R V Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514758 556 64820 T428 T N F E L P R T Q T D Y E N S
Chicken Gallus gallus XP_416045 912 106141 Y773 P Y G S H S S Y T M R G Y I N
Frog Xenopus laevis NP_001086810 896 105149 K750 Y Y A Y T Q D K D M P M S G Y
Zebra Danio Brachydanio rerio Q4V8U5 646 74505 A518 F S C V H P L A A V L V V L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 T781 E A T L N G Y T N W S L S Y F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 99.2 86.2 N.A. 90.3 36.5 N.A. 51 77.8 53 22.4 N.A. N.A. N.A. N.A. 40.8
Protein Similarity: 100 80.4 99.7 90.9 N.A. 95 56.3 N.A. 57.2 88.8 69.1 38.1 N.A. N.A. N.A. N.A. 60.2
P-Site Identity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 0 80 13.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 20 N.A. 20 86.6 13.3 26.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 10 10 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 37 0 0 10 10 10 0 19 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 37 0 10 0 0 % E
% Phe: 19 0 10 0 10 0 0 0 10 0 0 0 0 0 10 % F
% Gly: 0 0 55 0 0 10 0 0 0 0 0 55 0 10 0 % G
% His: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 10 10 0 10 0 0 10 10 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 64 0 10 0 0 0 % M
% Asn: 0 10 0 10 10 0 0 0 10 0 0 0 0 10 64 % N
% Pro: 55 0 0 0 0 19 0 0 0 0 19 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % R
% Ser: 0 10 0 10 0 19 46 0 0 0 10 0 19 0 10 % S
% Thr: 10 0 10 0 10 46 0 19 55 10 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 10 0 10 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 10 64 0 10 0 0 19 55 0 0 0 10 55 19 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _