KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
5.45
Human Site:
S1081
Identified Species:
10.91
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1081
C
Q
E
N
P
C
P
S
K
S
L
S
P
K
Q
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1081
C
Q
E
N
P
C
P
S
K
S
L
S
P
K
Q
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
I827
F
T
V
H
M
P
E
I
A
L
V
R
F
L
V
Dog
Lupus familis
XP_546733
1387
151432
W801
D
N
G
F
N
P
M
W
E
E
T
L
V
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
P1082
N
P
P
K
F
L
S
P
R
K
H
L
A
L
D
Rat
Rattus norvegicus
Q9QW07
1175
134478
H589
V
A
E
E
R
N
I
H
Y
N
M
S
S
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
A928
S
K
K
E
R
S
P
A
V
S
N
Q
T
K
R
Chicken
Gallus gallus
XP_422832
1901
211052
P1286
S
N
Q
E
S
L
L
P
A
E
T
V
P
L
I
Frog
Xenopus laevis
Q32NH8
758
87399
E172
M
M
N
V
D
M
S
E
H
H
A
F
R
L
F
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
K1076
S
Q
L
E
S
D
K
K
N
L
L
T
T
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
I732
A
E
S
T
V
D
G
I
I
A
G
T
V
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
T1314
D
T
S
T
D
H
V
T
D
N
K
S
S
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
0
0
N.A.
0
13.3
N.A.
20
6.6
0
20
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
6.6
26.6
N.A.
46.6
13.3
0
26.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
9
17
9
9
0
9
0
9
% A
% Cys:
17
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
17
17
0
0
9
0
0
0
0
9
9
% D
% Glu:
0
9
25
34
0
0
9
9
9
17
0
0
0
0
0
% E
% Phe:
9
0
0
9
9
0
0
0
0
0
0
9
9
17
9
% F
% Gly:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
9
0
9
0
9
9
9
9
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
9
17
9
0
0
0
0
0
17
% I
% Lys:
0
9
9
9
0
0
9
9
17
9
9
0
0
34
0
% K
% Leu:
0
0
9
0
0
17
9
0
0
17
25
17
0
34
0
% L
% Met:
9
9
0
0
9
9
9
0
0
0
9
0
0
0
0
% M
% Asn:
9
17
9
17
9
9
0
0
9
17
9
0
0
0
9
% N
% Pro:
0
9
9
0
17
17
25
17
0
0
0
0
25
0
0
% P
% Gln:
0
25
9
0
0
0
0
0
0
0
0
9
0
0
17
% Q
% Arg:
0
0
0
0
17
0
0
0
9
0
0
9
9
0
9
% R
% Ser:
25
0
17
0
17
9
17
17
0
25
0
34
17
9
0
% S
% Thr:
0
17
0
17
0
0
0
9
0
0
17
17
17
0
9
% T
% Val:
9
0
9
9
9
0
9
0
9
0
9
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _