KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
5.15
Human Site:
S1249
Identified Species:
10.3
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1249
F
C
K
G
K
S
K
S
S
F
L
C
S
S
P
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1249
F
C
K
G
K
S
K
S
S
F
L
C
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
D984
P
G
S
G
S
P
R
D
T
R
P
L
S
T
Q
Dog
Lupus familis
XP_546733
1387
151432
A958
S
P
G
P
V
L
E
A
S
A
P
E
E
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
A1241
L
S
Q
G
N
Q
K
A
S
F
L
C
S
S
P
Rat
Rattus norvegicus
Q9QW07
1175
134478
N746
R
T
R
M
V
M
N
N
G
L
N
P
V
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
E1085
T
T
V
F
S
S
P
E
T
T
E
Y
S
T
Y
Chicken
Gallus gallus
XP_422832
1901
211052
L1461
T
Q
S
S
K
S
P
L
F
S
T
P
D
S
A
Frog
Xenopus laevis
Q32NH8
758
87399
R329
G
Y
I
R
A
L
K
R
G
C
R
C
V
E
V
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
S1238
P
N
E
S
S
M
V
S
Q
G
S
S
P
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
L889
R
D
I
Q
L
S
V
L
T
D
E
A
E
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
H1515
Y
L
R
K
N
E
D
H
Y
N
L
S
L
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
13.3
6.6
N.A.
60
0
N.A.
13.3
20
13.3
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
20
N.A.
73.3
13.3
N.A.
26.6
20
13.3
13.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
17
0
9
0
9
0
9
9
% A
% Cys:
0
17
0
0
0
0
0
0
0
9
0
34
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
9
0
9
0
0
9
0
9
% D
% Glu:
0
0
9
0
0
9
9
9
0
0
17
9
17
9
0
% E
% Phe:
17
0
0
9
0
0
0
0
9
25
0
0
0
0
0
% F
% Gly:
9
9
9
34
0
0
0
0
17
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
17
9
25
0
34
0
0
0
0
0
0
0
9
% K
% Leu:
9
9
0
0
9
17
0
17
0
9
34
9
9
0
9
% L
% Met:
0
0
0
9
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
17
0
9
9
0
9
9
0
0
0
9
% N
% Pro:
17
9
0
9
0
9
17
0
0
0
17
17
9
9
25
% P
% Gln:
0
9
9
9
0
9
0
0
9
0
0
0
0
0
9
% Q
% Arg:
17
0
17
9
0
0
9
9
0
9
9
0
0
0
0
% R
% Ser:
9
9
17
17
25
42
0
25
34
9
9
17
42
34
0
% S
% Thr:
17
17
0
0
0
0
0
0
25
9
9
0
0
17
0
% T
% Val:
0
0
9
0
17
0
17
0
0
0
0
0
17
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
0
9
0
0
9
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _