KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
9.09
Human Site:
S1262
Identified Species:
18.18
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1262
S
P
E
L
I
A
L
S
S
S
E
T
T
K
H
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1262
S
P
E
P
I
A
L
S
S
S
E
T
T
K
H
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
P997
T
Q
R
P
L
P
P
P
C
S
L
E
T
I
A
Dog
Lupus familis
XP_546733
1387
151432
D971
P
G
S
R
S
P
R
D
T
R
P
F
S
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
S1254
S
P
E
L
N
K
L
S
S
V
E
T
T
K
L
Rat
Rattus norvegicus
Q9QW07
1175
134478
F759
Y
N
E
E
S
F
V
F
R
K
V
I
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
A1098
T
Y
T
I
V
H
E
A
A
P
T
L
L
S
K
Chicken
Gallus gallus
XP_422832
1901
211052
E1474
S
A
V
F
P
S
P
E
T
A
E
Y
S
V
Y
Frog
Xenopus laevis
Q32NH8
758
87399
P342
E
V
D
T
W
D
G
P
N
G
E
P
I
V
Y
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
T1251
I
K
K
P
L
E
W
T
A
Q
R
N
P
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
D902
A
L
G
S
A
D
E
D
L
S
K
S
F
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
M1528
V
D
H
S
Q
G
Y
M
Q
Y
P
E
G
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
93.3
13.3
0
N.A.
73.3
6.6
N.A.
0
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
93.3
26.6
13.3
N.A.
73.3
13.3
N.A.
33.3
46.6
26.6
33.3
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
17
0
9
17
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
17
0
17
0
0
0
0
0
0
9
% D
% Glu:
9
0
34
9
0
9
17
9
0
0
42
17
0
0
17
% E
% Phe:
0
0
0
9
0
9
0
9
0
0
0
9
9
0
9
% F
% Gly:
0
9
9
0
0
9
9
0
0
9
0
0
9
0
0
% G
% His:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
17
% H
% Ile:
9
0
0
9
17
0
0
0
0
0
0
9
9
9
0
% I
% Lys:
0
9
9
0
0
9
0
0
0
9
9
0
0
34
9
% K
% Leu:
0
9
0
17
17
0
25
0
9
0
9
9
17
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
9
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
9
25
0
25
9
17
17
17
0
9
17
9
9
9
0
% P
% Gln:
0
9
0
0
9
0
0
0
9
9
0
0
0
0
9
% Q
% Arg:
0
0
9
9
0
0
9
0
9
9
9
0
0
9
0
% R
% Ser:
34
0
9
17
17
9
0
25
25
34
0
9
17
9
0
% S
% Thr:
17
0
9
9
0
0
0
9
17
0
9
25
34
0
0
% T
% Val:
9
9
9
0
9
0
9
0
0
9
9
0
0
25
0
% V
% Trp:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
9
0
0
9
0
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _