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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
6.36
Human Site:
S1264
Identified Species:
12.73
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1264
E
L
I
A
L
S
S
S
E
T
T
K
H
A
T
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1264
E
P
I
A
L
S
S
S
E
T
T
K
H
A
T
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
S999
R
P
L
P
P
P
C
S
L
E
T
I
A
E
E
Dog
Lupus familis
XP_546733
1387
151432
R973
S
R
S
P
R
D
T
R
P
F
S
M
Q
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
V1256
E
L
N
K
L
S
S
V
E
T
T
K
L
A
N
Rat
Rattus norvegicus
Q9QW07
1175
134478
K761
E
E
S
F
V
F
R
K
V
I
L
P
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
P1100
T
I
V
H
E
A
A
P
T
L
L
S
K
C
H
Chicken
Gallus gallus
XP_422832
1901
211052
A1476
V
F
P
S
P
E
T
A
E
Y
S
V
Y
T
I
Frog
Xenopus laevis
Q32NH8
758
87399
G344
D
T
W
D
G
P
N
G
E
P
I
V
Y
H
G
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
Q1253
K
P
L
E
W
T
A
Q
R
N
P
K
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
S904
G
S
A
D
E
D
L
S
K
S
F
V
F
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
Y1530
H
S
Q
G
Y
M
Q
Y
P
E
G
R
E
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
93.3
13.3
6.6
N.A.
66.6
6.6
N.A.
0
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
93.3
20
20
N.A.
66.6
13.3
N.A.
26.6
40
26.6
46.6
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
9
17
9
0
0
0
0
9
25
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
17
0
17
0
0
0
0
0
0
9
0
0
% D
% Glu:
34
9
0
9
17
9
0
0
42
17
0
0
17
9
9
% E
% Phe:
0
9
0
9
0
9
0
0
0
9
9
0
9
0
0
% F
% Gly:
9
0
0
9
9
0
0
9
0
0
9
0
0
0
9
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
17
9
9
% H
% Ile:
0
9
17
0
0
0
0
0
0
9
9
9
0
0
9
% I
% Lys:
9
0
0
9
0
0
0
9
9
0
0
34
9
0
0
% K
% Leu:
0
17
17
0
25
0
9
0
9
9
17
0
9
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
0
9
0
0
0
0
9
% N
% Pro:
0
25
9
17
17
17
0
9
17
9
9
9
0
0
0
% P
% Gln:
0
0
9
0
0
0
9
9
0
0
0
0
9
0
17
% Q
% Arg:
9
9
0
0
9
0
9
9
9
0
0
9
0
17
0
% R
% Ser:
9
17
17
9
0
25
25
34
0
9
17
9
0
9
9
% S
% Thr:
9
9
0
0
0
9
17
0
9
25
34
0
0
9
25
% T
% Val:
9
0
9
0
9
0
0
9
9
0
0
25
0
9
0
% V
% Trp:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
9
0
9
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _