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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
5.15
Human Site:
S1307
Identified Species:
10.3
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1307
L
E
S
N
L
P
G
S
P
N
T
S
R
G
W
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1307
L
E
S
N
L
P
G
S
P
N
T
S
H
G
W
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
P1042
G
A
D
V
T
S
P
P
E
D
T
E
E
H
R
Dog
Lupus familis
XP_546733
1387
151432
L1016
S
P
S
P
G
G
P
L
C
A
S
G
P
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
G1299
V
I
E
G
N
L
P
G
F
P
D
A
S
P
G
Rat
Rattus norvegicus
Q9QW07
1175
134478
E804
R
H
I
S
L
R
N
E
G
N
K
P
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
N1143
C
H
L
S
P
Q
V
N
H
V
R
V
W
K
T
Chicken
Gallus gallus
XP_422832
1901
211052
S1519
N
L
P
S
S
F
C
S
S
P
F
S
L
L
N
Frog
Xenopus laevis
Q32NH8
758
87399
C387
I
L
S
L
E
N
H
C
G
V
E
Q
Q
D
A
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
D1296
D
R
F
L
M
C
Q
D
S
V
S
S
S
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
V947
A
M
S
V
D
V
T
V
D
R
T
D
G
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
G1573
P
E
Y
C
E
S
E
G
Q
M
D
S
L
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
93.3
6.6
13.3
N.A.
0
13.3
N.A.
0
13.3
6.6
6.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
13.3
20
N.A.
13.3
20
N.A.
13.3
20
20
20
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
9
0
9
0
0
9
% A
% Cys:
9
0
0
9
0
9
9
9
9
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
9
0
0
9
9
9
17
9
0
9
0
% D
% Glu:
0
25
9
0
17
0
9
9
9
0
9
9
9
0
0
% E
% Phe:
0
0
9
0
0
9
0
0
9
0
9
0
0
0
0
% F
% Gly:
9
0
0
9
9
9
17
17
17
0
0
9
9
34
9
% G
% His:
0
17
0
0
0
0
9
0
9
0
0
0
9
9
0
% H
% Ile:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% K
% Leu:
17
17
9
17
25
9
0
9
0
0
0
0
25
17
9
% L
% Met:
0
9
0
0
9
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
9
0
0
17
9
9
9
9
0
25
0
0
0
0
17
% N
% Pro:
9
9
9
9
9
17
25
9
17
17
0
9
9
9
0
% P
% Gln:
0
0
0
0
0
9
9
0
9
0
0
9
9
0
0
% Q
% Arg:
9
9
0
0
0
9
0
0
0
9
9
0
9
0
17
% R
% Ser:
9
0
42
25
9
17
0
25
17
0
17
42
17
17
0
% S
% Thr:
0
0
0
0
9
0
9
0
0
0
34
0
0
0
17
% T
% Val:
9
0
0
17
0
9
9
9
0
25
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
17
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _