KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
6.97
Human Site:
S1318
Identified Species:
13.94
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1318
S
R
G
W
L
P
K
S
P
T
K
G
E
D
W
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1318
S
H
G
W
L
P
K
S
P
T
K
G
E
D
W
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
P1053
E
E
H
R
D
S
R
P
R
P
C
N
G
K
R
Dog
Lupus familis
XP_546733
1387
151432
S1027
G
P
G
T
K
V
T
S
P
P
A
V
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
K1310
A
S
P
G
Q
F
P
K
S
P
T
H
G
E
D
Rat
Rattus norvegicus
Q9QW07
1175
134478
F815
P
L
S
L
P
T
I
F
C
N
I
V
L
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
C1154
V
W
K
T
F
E
N
C
S
P
S
T
L
D
D
Chicken
Gallus gallus
XP_422832
1901
211052
Q1530
S
L
L
N
A
N
P
Q
R
K
C
E
T
S
W
Frog
Xenopus laevis
Q32NH8
758
87399
H398
Q
Q
D
A
M
A
Q
H
L
K
S
I
L
G
N
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
I1307
S
S
L
M
E
L
E
I
N
V
D
G
D
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
S958
D
G
G
R
G
E
D
S
I
S
I
V
A
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S1584
S
L
S
N
V
V
D
S
M
F
D
L
V
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
93.3
0
20
N.A.
0
0
N.A.
6.6
13.3
0
13.3
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
6.6
20
N.A.
13.3
0
N.A.
6.6
13.3
20
26.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
9
0
0
0
0
9
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
17
0
0
0
0
% C
% Asp:
9
0
9
0
9
0
17
0
0
0
17
0
9
25
17
% D
% Glu:
9
9
0
0
9
17
9
0
0
0
0
9
17
9
0
% E
% Phe:
0
0
0
0
9
9
0
9
0
9
0
0
0
0
0
% F
% Gly:
9
9
34
9
9
0
0
0
0
0
0
25
17
9
9
% G
% His:
0
9
9
0
0
0
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
9
0
17
9
0
0
0
% I
% Lys:
0
0
9
0
9
0
17
9
0
17
17
0
0
17
0
% K
% Leu:
0
25
17
9
17
9
0
0
9
0
0
9
25
9
9
% L
% Met:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
9
9
0
9
9
0
9
0
0
9
% N
% Pro:
9
9
9
0
9
17
17
9
25
34
0
0
0
17
0
% P
% Gln:
9
9
0
0
9
0
9
9
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
17
0
0
9
0
17
0
0
0
0
0
9
% R
% Ser:
42
17
17
0
0
9
0
42
17
9
17
0
0
9
17
% S
% Thr:
0
0
0
17
0
9
9
0
0
17
9
9
17
0
9
% T
% Val:
9
0
0
0
9
17
0
0
0
9
0
25
9
0
0
% V
% Trp:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
25
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _