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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
5.76
Human Site:
S1433
Identified Species:
11.52
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S1433
D
V
K
T
Q
S
I
S
Y
L
A
Y
Q
G
A
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S1433
D
V
K
T
Q
S
I
S
Y
L
A
Y
Q
G
A
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
E1167
L
G
L
G
R
S
R
E
S
L
L
G
A
H
V
Dog
Lupus familis
XP_546733
1387
151432
I1141
V
S
S
S
D
T
V
I
D
L
S
L
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
L1425
K
N
H
S
I
S
H
L
T
Y
Q
G
A
G
F
Rat
Rattus norvegicus
Q9QW07
1175
134478
L929
L
K
Q
M
K
A
Y
L
K
H
L
K
K
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
Q1268
F
V
H
N
G
Y
L
Q
T
S
G
G
K
A
G
Chicken
Gallus gallus
XP_422832
1901
211052
F1644
T
A
G
S
K
L
P
F
P
A
C
E
N
V
G
Frog
Xenopus laevis
Q32NH8
758
87399
E512
R
A
H
Y
I
L
Y
E
M
S
S
V
T
E
Y
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
C1444
C
L
T
K
T
K
G
C
N
N
S
I
E
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
G1072
L
S
P
H
S
E
P
G
V
E
I
P
A
C
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S1808
K
Q
E
E
E
D
E
S
K
E
S
N
G
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
13.3
13.3
N.A.
13.3
0
N.A.
6.6
0
0
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
40
N.A.
20
26.6
N.A.
20
13.3
6.6
20
N.A.
0
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
9
0
0
0
9
17
0
25
9
17
% A
% Cys:
9
0
0
0
0
0
0
9
0
0
9
0
0
9
0
% C
% Asp:
17
0
0
0
9
9
0
0
9
0
0
0
0
0
9
% D
% Glu:
0
0
9
9
9
9
9
17
0
17
0
9
9
9
0
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
9
9
9
9
0
9
9
0
0
9
25
9
34
17
% G
% His:
0
0
25
9
0
0
9
0
0
9
0
0
0
9
0
% H
% Ile:
0
0
0
0
17
0
17
9
0
0
9
9
0
0
0
% I
% Lys:
17
9
17
9
17
9
0
0
17
0
0
9
17
0
0
% K
% Leu:
25
9
9
0
0
17
9
17
0
34
17
9
0
0
9
% L
% Met:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
9
0
9
0
0
0
0
9
9
0
9
9
0
0
% N
% Pro:
0
0
9
0
0
0
17
0
9
0
0
9
9
0
9
% P
% Gln:
0
9
9
0
17
0
0
9
0
0
9
0
17
9
9
% Q
% Arg:
9
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% R
% Ser:
0
17
9
25
9
34
0
25
9
17
34
0
0
0
0
% S
% Thr:
9
0
9
17
9
9
0
0
17
0
0
0
9
0
0
% T
% Val:
9
25
0
0
0
0
9
0
9
0
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
17
0
17
9
0
17
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _