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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
23.33
Human Site:
S325
Identified Species:
46.67
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S325
L
T
G
D
Q
L
L
S
Q
S
K
V
D
M
Y
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S325
L
T
G
D
Q
L
L
S
Q
S
K
V
D
M
Y
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
Y125
P
N
C
C
F
S
I
Y
H
G
S
H
H
E
S
Dog
Lupus familis
XP_546733
1387
151432
W98
S
G
D
E
A
R
T
W
V
T
G
L
R
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
S325
L
T
G
D
Q
L
L
S
Q
S
K
V
D
M
Y
Rat
Rattus norvegicus
Q9QW07
1175
134478
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
S226
L
S
I
E
N
H
C
S
I
Q
Q
Q
K
K
I
Chicken
Gallus gallus
XP_422832
1901
211052
S550
L
T
G
D
Q
L
L
S
Q
S
R
V
E
M
Y
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
S307
L
T
G
D
Q
L
L
S
H
S
K
T
D
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
D30
G
E
K
F
I
R
W
D
D
D
S
G
T
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S425
L
L
G
D
Q
L
M
S
Q
S
S
V
D
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
0
0
N.A.
100
0
N.A.
13.3
86.6
0
86.6
N.A.
0
N.A.
N.A.
73.3
P-Site Similarity:
100
100
6.6
20
N.A.
100
0
N.A.
33.3
100
0
86.6
N.A.
0
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
50
0
0
0
9
9
9
0
0
42
0
0
% D
% Glu:
0
9
0
17
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
50
0
0
0
0
0
0
9
9
9
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
17
0
0
9
9
0
0
% H
% Ile:
0
0
9
0
9
0
9
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
34
0
9
9
0
% K
% Leu:
59
9
0
0
0
50
42
0
0
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
42
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
0
42
9
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
17
0
0
0
0
9
0
9
0
0
% R
% Ser:
9
9
0
0
0
9
0
59
0
50
25
0
0
0
9
% S
% Thr:
0
42
0
0
0
0
9
0
0
9
0
9
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
42
0
9
0
% V
% Trp:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _