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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
17.58
Human Site:
S497
Identified Species:
35.15
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
S497
F
I
R
K
K
L
E
S
L
L
K
E
S
Q
I
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
S497
F
I
R
K
K
L
E
S
L
L
K
E
S
Q
I
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
Q282
G
V
T
L
E
S
C
Q
D
I
I
E
Q
F
E
Dog
Lupus familis
XP_546733
1387
151432
G256
E
V
E
Q
K
M
A
G
V
T
L
E
S
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
S497
F
I
R
K
K
L
E
S
L
L
K
E
S
Q
I
Rat
Rattus norvegicus
Q9QW07
1175
134478
F44
C
L
F
K
V
D
E
F
G
F
F
L
T
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
K383
S
I
M
S
N
F
G
K
H
K
K
T
S
K
S
Chicken
Gallus gallus
XP_422832
1901
211052
S722
F
I
R
T
K
L
E
S
L
L
K
E
S
Q
I
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
S479
H
I
R
K
K
L
D
S
L
M
K
E
S
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
E187
K
E
D
R
K
R
V
E
K
A
L
D
V
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
P598
L
A
L
M
R
K
K
P
I
S
P
S
Q
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
6.6
20
N.A.
100
13.3
N.A.
20
93.3
0
80
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
46.6
N.A.
100
26.6
N.A.
26.6
93.3
0
93.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
9
% A
% Cys:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
9
0
0
9
9
0
9
0
0
9
0
0
0
% D
% Glu:
9
9
9
0
9
0
42
9
0
0
0
59
0
0
9
% E
% Phe:
34
0
9
0
0
9
0
9
0
9
9
0
0
9
0
% F
% Gly:
9
0
0
0
0
0
9
9
9
0
0
0
0
0
9
% G
% His:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
0
0
9
9
9
0
0
0
42
% I
% Lys:
9
0
0
42
59
9
9
9
9
9
50
0
0
9
9
% K
% Leu:
9
9
9
9
0
42
0
0
42
34
17
9
0
0
0
% L
% Met:
0
0
9
9
0
9
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
0
17
50
0
% Q
% Arg:
0
0
42
9
9
9
0
0
0
0
0
0
0
0
9
% R
% Ser:
9
0
0
9
0
9
0
42
0
9
0
9
59
0
9
% S
% Thr:
0
0
9
9
0
0
0
0
0
9
0
9
9
9
0
% T
% Val:
0
17
0
0
9
0
9
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _