KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
11.21
Human Site:
T1521
Identified Species:
22.42
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
T1521
I
S
K
S
F
V
T
T
G
I
R
D
K
K
G
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
T1521
I
S
K
S
F
V
T
T
G
I
R
D
K
K
G
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
P1246
L
V
G
L
Q
D
C
P
V
A
A
K
S
K
S
Dog
Lupus familis
XP_546733
1387
151432
P1220
R
P
L
V
P
R
L
P
W
G
H
L
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
N1511
I
S
R
S
F
V
T
N
G
I
R
D
K
S
V
Rat
Rattus norvegicus
Q9QW07
1175
134478
D1008
K
I
Q
T
L
T
S
D
H
K
S
K
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
K1347
I
T
A
G
M
R
D
K
R
I
V
A
V
K
A
Chicken
Gallus gallus
XP_422832
1901
211052
S1729
I
S
R
S
F
V
T
S
G
M
R
D
K
K
L
Frog
Xenopus laevis
Q32NH8
758
87399
R591
G
L
F
R
Q
N
A
R
C
G
Y
V
L
K
P
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
P1528
I
S
R
S
F
V
T
P
A
M
Q
D
Q
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
Q1151
L
K
T
S
Q
T
G
Q
T
K
Q
L
K
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S1914
V
D
E
S
A
L
S
S
V
V
V
F
T
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
6.6
0
N.A.
73.3
6.6
N.A.
20
73.3
6.6
46.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
0
N.A.
80
26.6
N.A.
26.6
93.3
6.6
80
N.A.
26.6
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
9
9
9
9
0
9
17
% A
% Cys:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
9
9
0
0
0
42
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
9
0
42
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
0
9
9
0
0
9
0
34
17
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
50
9
0
0
0
0
0
0
0
34
0
0
0
0
0
% I
% Lys:
9
9
17
0
0
0
0
9
0
17
0
17
42
59
0
% K
% Leu:
17
9
9
9
9
9
9
0
0
0
0
17
9
9
9
% L
% Met:
0
0
0
0
9
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
9
0
0
25
0
0
0
0
9
0
9
% P
% Gln:
0
0
9
0
25
0
0
9
0
0
17
0
9
0
0
% Q
% Arg:
9
0
25
9
0
17
0
9
9
0
34
0
0
9
9
% R
% Ser:
0
42
0
59
0
0
17
17
0
0
9
0
9
9
17
% S
% Thr:
0
9
9
9
0
17
42
17
9
0
0
0
9
0
0
% T
% Val:
9
9
0
9
0
42
0
0
17
9
17
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _