KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
10
Human Site:
T558
Identified Species:
20
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
T558
N
F
G
K
H
K
K
T
T
K
S
R
S
K
S
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
T558
N
F
G
K
H
K
K
T
T
K
S
R
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
T343
F
I
T
S
S
H
N
T
Y
L
V
G
D
Q
L
Dog
Lupus familis
XP_546733
1387
151432
F317
T
R
P
L
S
H
Y
F
I
T
S
S
H
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
K558
N
F
G
K
H
K
Q
K
A
T
K
S
R
S
K
Rat
Rattus norvegicus
Q9QW07
1175
134478
D105
L
C
V
C
S
G
T
D
L
V
N
I
G
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
Q444
Y
T
N
S
V
A
A
Q
D
I
V
D
D
G
T
Chicken
Gallus gallus
XP_422832
1901
211052
T783
N
F
G
K
H
K
K
T
G
K
A
T
S
K
C
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
S540
K
H
K
R
H
S
K
S
R
L
K
C
Q
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
V248
C
M
S
I
A
Q
L
V
E
F
L
N
K
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
E659
S
D
N
N
S
S
M
E
Y
D
R
S
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
6.6
6.6
N.A.
40
0
N.A.
0
73.3
0
13.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
46.6
13.3
N.A.
6.6
80
0
26.6
N.A.
6.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
9
0
9
0
9
0
0
0
0
% A
% Cys:
9
9
0
9
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
9
0
0
0
0
0
9
9
9
0
9
17
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
9
34
0
0
0
0
0
9
0
9
0
0
0
9
0
% F
% Gly:
0
0
34
0
0
9
0
0
9
0
0
9
9
9
0
% G
% His:
0
9
0
0
42
17
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
9
9
0
9
0
0
0
% I
% Lys:
9
0
9
34
0
34
34
9
0
25
17
0
9
25
9
% K
% Leu:
9
0
0
9
0
0
9
0
9
17
9
0
0
0
9
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
17
9
0
0
9
0
0
0
9
9
0
9
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
9
0
0
0
0
9
9
9
% Q
% Arg:
0
9
0
9
0
0
0
0
9
0
9
17
9
0
9
% R
% Ser:
9
0
9
17
34
17
0
9
0
0
25
25
34
25
17
% S
% Thr:
9
9
9
0
0
0
9
34
17
17
0
9
0
9
25
% T
% Val:
0
0
9
0
9
0
0
9
0
9
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _