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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
12.12
Human Site:
T622
Identified Species:
24.24
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
T622
D
I
V
D
D
G
T
T
G
N
V
L
S
F
S
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
T622
D
I
V
D
D
G
T
T
G
N
V
L
S
F
S
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
A407
I
E
T
I
N
K
Y
A
F
I
K
N
E
Y
P
Dog
Lupus familis
XP_546733
1387
151432
I381
K
I
L
F
R
D
V
I
E
T
I
N
K
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
T622
Q
D
I
V
D
D
G
T
T
G
N
V
L
S
F
Rat
Rattus norvegicus
Q9QW07
1175
134478
I169
G
K
I
P
V
R
S
I
T
R
T
F
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
Q508
P
Y
W
N
A
G
C
Q
L
V
A
L
N
Y
Q
Chicken
Gallus gallus
XP_422832
1901
211052
T847
D
I
V
D
D
G
S
T
G
N
V
L
S
F
S
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
S604
G
S
P
C
N
V
L
S
F
S
E
A
R
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
S312
D
N
P
I
M
A
P
S
K
L
D
L
C
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
C723
G
F
P
E
N
M
P
C
W
E
L
P
S
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
0
6.6
N.A.
13.3
0
N.A.
13.3
93.3
0
0
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
33.3
N.A.
26.6
20
N.A.
33.3
100
0
20
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
9
0
0
9
9
9
9
9
% A
% Cys:
0
0
0
9
0
0
9
9
0
0
0
0
9
0
0
% C
% Asp:
34
9
0
25
34
17
0
0
0
0
9
0
0
9
9
% D
% Glu:
0
9
0
9
0
0
0
0
9
9
9
0
9
0
0
% E
% Phe:
0
9
0
9
0
0
0
0
17
0
0
9
0
25
9
% F
% Gly:
25
0
0
0
0
34
9
0
25
9
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
34
17
17
0
0
0
17
0
9
9
0
0
0
0
% I
% Lys:
9
9
0
0
0
9
0
0
9
0
9
0
9
0
0
% K
% Leu:
0
0
9
0
0
0
9
0
9
9
9
42
9
9
0
% L
% Met:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
25
0
0
0
0
25
9
17
9
0
0
% N
% Pro:
9
0
25
9
0
0
17
0
0
0
0
9
0
0
9
% P
% Gln:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
17
% Q
% Arg:
0
0
0
0
9
9
0
0
0
9
0
0
9
0
0
% R
% Ser:
0
9
0
0
0
0
17
17
0
9
0
0
34
17
25
% S
% Thr:
0
0
9
0
0
0
17
34
17
9
9
0
0
0
0
% T
% Val:
0
0
25
9
9
9
9
0
0
9
25
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
0
0
0
0
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _