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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
22.42
Human Site:
Y317
Identified Species:
44.85
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
Y317
I
A
S
S
H
N
T
Y
L
T
G
D
Q
L
L
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
Y317
I
A
S
S
H
N
T
Y
L
T
G
D
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
D117
R
Y
P
D
G
S
F
D
P
N
C
C
F
S
I
Dog
Lupus familis
XP_546733
1387
151432
P90
E
S
L
D
L
V
S
P
S
G
D
E
A
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
Y317
I
A
S
S
H
N
T
Y
L
T
G
D
Q
L
L
Rat
Rattus norvegicus
Q9QW07
1175
134478
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
I218
L
K
N
E
F
P
V
I
L
S
I
E
N
H
C
Chicken
Gallus gallus
XP_422832
1901
211052
Y542
I
A
S
S
H
N
T
Y
L
T
G
D
Q
L
L
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
Y299
I
A
S
S
H
N
T
Y
L
T
G
D
Q
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
D22
E
V
P
Q
A
L
Q
D
G
E
K
F
I
R
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
Y417
I
A
S
S
H
N
T
Y
L
L
G
D
Q
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
0
0
N.A.
100
0
N.A.
6.6
100
0
100
N.A.
0
N.A.
N.A.
86.6
P-Site Similarity:
100
100
13.3
20
N.A.
100
0
N.A.
33.3
100
0
100
N.A.
0
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
9
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% C
% Asp:
0
0
0
17
0
0
0
17
0
0
9
50
0
0
0
% D
% Glu:
17
0
0
9
0
0
0
0
0
9
0
17
0
0
0
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
9
9
50
0
0
0
0
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
50
0
0
0
0
0
0
9
0
0
9
0
9
0
9
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
9
0
9
0
9
9
0
0
59
9
0
0
0
50
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
50
0
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
17
0
0
9
0
9
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
50
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% R
% Ser:
0
9
50
50
0
9
9
0
9
9
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
50
0
0
42
0
0
0
0
9
% T
% Val:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _