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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH1
All Species:
4.55
Human Site:
Y586
Identified Species:
9.09
UniProt:
Q4KWH8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4KWH8
NP_001124432.1
1693
189223
Y586
G
K
E
G
G
Q
L
Y
R
L
G
R
R
R
K
Chimpanzee
Pan troglodytes
XP_001149022
1693
189279
Y586
G
K
E
G
G
Q
L
Y
R
L
G
R
R
R
K
Rhesus Macaque
Macaca mulatta
XP_001085547
1413
154924
E371
Q
A
G
C
R
C
V
E
V
D
C
W
D
G
P
Dog
Lupus familis
XP_546733
1387
151432
Q345
D
M
Y
A
W
V
L
Q
A
G
C
R
C
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q4KWH5
1682
187725
L586
P
G
K
E
G
G
Q
L
Y
R
L
G
R
R
R
Rat
Rattus norvegicus
Q9QW07
1175
134478
I133
V
E
G
L
R
S
I
I
H
N
F
R
A
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506729
1514
168422
E472
Q
V
V
Q
Q
K
S
E
Q
F
M
I
Y
N
Q
Chicken
Gallus gallus
XP_422832
1901
211052
H811
G
K
E
A
G
Q
L
H
R
L
T
R
R
R
K
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
XP_694841
1715
193536
R568
Q
F
N
R
C
G
R
R
R
K
T
I
K
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
L276
N
P
A
R
A
K
E
L
I
Q
Q
Y
E
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
M687
A
E
Q
A
K
Q
R
M
S
S
A
N
R
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
45.1
44.7
N.A.
85.9
24.6
N.A.
63.6
59.5
21.4
53.9
N.A.
23.3
N.A.
N.A.
27
Protein Similarity:
100
99.4
58.3
57.4
N.A.
90.1
40
N.A.
71.8
68.9
31.6
67.3
N.A.
39.5
N.A.
N.A.
41
P-Site Identity:
100
100
0
13.3
N.A.
20
6.6
N.A.
0
80
0
6.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
20
N.A.
33.3
20
N.A.
20
86.6
0
13.3
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
25
9
0
0
0
9
0
9
0
9
0
0
% A
% Cys:
0
0
0
9
9
9
0
0
0
0
17
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
0
17
25
9
0
0
9
17
0
0
0
0
9
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% F
% Gly:
25
9
17
17
34
17
0
0
0
9
17
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
9
0
0
17
0
0
0
% I
% Lys:
0
25
9
0
9
17
0
0
0
9
0
0
9
9
25
% K
% Leu:
0
0
0
9
0
0
34
17
0
25
9
0
0
9
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
9
0
9
0
17
17
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
25
0
9
9
9
34
9
9
9
9
9
0
0
0
9
% Q
% Arg:
0
0
0
17
17
0
17
9
34
9
0
42
42
34
17
% R
% Ser:
0
0
0
0
0
9
9
0
9
9
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% T
% Val:
9
9
9
0
0
9
9
0
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
17
9
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _