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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FILIP1L
All Species:
13.03
Human Site:
S421
Identified Species:
35.83
UniProt:
Q4L180
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4L180
NP_001035924.1
1135
130382
S421
K
L
E
V
E
K
L
S
K
R
I
M
A
L
E
Chimpanzee
Pan troglodytes
XP_516621
1352
154470
S421
K
L
E
V
E
K
L
S
K
R
I
M
A
L
E
Rhesus Macaque
Macaca mulatta
XP_001090550
1135
130382
S421
K
L
E
V
E
K
L
S
K
R
I
M
A
L
E
Dog
Lupus familis
XP_535715
1130
129897
N418
K
L
E
V
E
K
L
N
K
R
I
M
A
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6L0
1131
129754
S419
K
L
E
V
D
K
L
S
V
R
I
T
A
L
E
Rat
Rattus norvegicus
Q8K4T4
1212
137734
Q428
R
L
E
V
E
K
L
Q
K
R
M
S
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519034
1137
129557
N421
K
V
E
V
D
K
L
N
K
R
I
M
E
L
E
Chicken
Gallus gallus
XP_419877
1176
134725
Q428
K
L
E
V
E
K
L
Q
K
R
M
S
E
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KNA5
1129
129722
N413
K
A
E
V
D
K
L
N
H
R
I
M
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
98.1
92.2
N.A.
87.8
44.4
N.A.
78.7
46
N.A.
57.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.8
98.7
95.5
N.A.
93.4
62.7
N.A.
86.9
64.8
N.A.
74.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
66.6
N.A.
73.3
73.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
93.3
80
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
0
0
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
100
0
67
0
0
0
0
0
0
0
45
0
89
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% I
% Lys:
89
0
0
0
0
100
0
0
78
0
0
0
0
0
0
% K
% Leu:
0
78
0
0
0
0
100
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
23
67
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
45
0
0
0
23
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
12
0
100
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _