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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AASDH
All Species:
0.91
Human Site:
S585
Identified Species:
1.67
UniProt:
Q4L235
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4L235
NP_861522.2
1098
122597
S585
D
E
S
L
F
L
N
S
G
G
D
S
L
K
S
Chimpanzee
Pan troglodytes
XP_526619
419
46896
Rhesus Macaque
Macaca mulatta
XP_001084597
517
57678
Dog
Lupus familis
XP_539278
1094
122201
N581
S
D
E
S
L
F
L
N
S
G
G
D
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80WC9
1100
121551
F584
K
V
P
A
N
S
V
F
L
D
S
G
G
D
S
Rat
Rattus norvegicus
XP_344231
1099
121246
L583
V
P
D
N
S
V
F
L
D
S
G
G
D
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521114
1121
120374
L605
K
L
N
G
A
C
K
L
R
G
E
E
Q
L
W
Chicken
Gallus gallus
XP_420697
1128
125269
I608
A
L
Q
F
Y
D
E
I
E
M
L
V
G
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RG49
1149
125488
V617
R
L
F
D
D
I
T
V
A
M
G
T
T
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLL0
1012
113065
R502
S
I
A
E
Q
P
D
R
F
V
Y
L
Q
H
F
Honey Bee
Apis mellifera
XP_395233
653
74131
R143
L
S
N
N
T
S
L
R
A
I
L
F
G
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325887
1058
116913
S547
L
Y
N
F
P
T
P
S
K
L
H
A
A
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198442
1040
115575
H529
G
D
S
L
A
A
A
H
L
S
H
S
L
G
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.4
44.9
85.4
N.A.
72.8
71.8
N.A.
53.8
57.4
N.A.
41.9
N.A.
24.2
23.1
N.A.
N.A.
Protein Similarity:
100
37.7
45.8
91.5
N.A.
84.4
83.7
N.A.
69.5
73.4
N.A.
60.1
N.A.
44.6
38.7
N.A.
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
6.6
0
N.A.
6.6
0
N.A.
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
0
0
20
N.A.
6.6
6.6
N.A.
20
13.3
N.A.
13.3
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
22.7
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
43.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
16
8
8
0
16
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
8
8
8
8
8
0
8
8
8
8
8
8
0
% D
% Glu:
0
8
8
8
0
0
8
0
8
0
8
8
0
0
8
% E
% Phe:
0
0
8
16
8
8
8
8
8
0
0
8
0
0
8
% F
% Gly:
8
0
0
8
0
0
0
0
8
24
24
16
24
16
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
16
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
8
0
8
0
0
0
0
8
% I
% Lys:
16
0
0
0
0
0
8
0
8
0
0
0
0
8
8
% K
% Leu:
16
24
0
16
8
8
16
16
16
8
16
8
16
24
16
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
24
16
8
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
8
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
8
0
0
0
0
0
0
16
8
0
0
0
0
8
0
% R
% Ser:
16
8
16
8
8
16
0
16
8
16
8
16
8
16
16
% S
% Thr:
0
0
0
0
8
8
8
0
0
0
0
8
8
0
0
% T
% Val:
8
8
0
0
0
8
8
8
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _