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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AASDH
All Species:
0.61
Human Site:
S641
Identified Species:
1.11
UniProt:
Q4L235
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4L235
NP_861522.2
1098
122597
S641
E
D
V
T
F
R
K
S
C
A
T
K
R
K
L
Chimpanzee
Pan troglodytes
XP_526619
419
46896
Rhesus Macaque
Macaca mulatta
XP_001084597
517
57678
F63
N
Q
E
K
L
I
L
F
M
V
S
K
D
A
S
Dog
Lupus familis
XP_539278
1094
122201
K637
D
E
D
L
V
F
S
K
N
Y
A
T
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80WC9
1100
121551
A640
F
T
P
E
D
R
K
A
N
R
S
Y
T
T
K
Rat
Rattus norvegicus
XP_344231
1099
121246
D639
T
R
E
D
L
K
G
D
R
R
Y
T
T
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521114
1121
120374
T661
E
V
E
G
L
V
G
T
A
V
P
G
L
L
E
Chicken
Gallus gallus
XP_420697
1128
125269
E664
L
S
K
N
N
G
E
E
I
H
R
K
Y
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RG49
1149
125488
K673
A
S
G
K
R
Q
H
K
E
M
T
T
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLL0
1012
113065
K558
P
D
D
S
A
S
K
K
Q
R
L
D
D
A
A
Honey Bee
Apis mellifera
XP_395233
653
74131
Y199
G
G
Q
F
N
V
H
Y
L
G
Q
V
L
S
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002325887
1058
116913
P603
G
L
K
S
M
K
Q
P
S
K
N
P
H
Q
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198442
1040
115575
L585
E
S
Q
N
G
N
G
L
V
S
R
T
V
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.4
44.9
85.4
N.A.
72.8
71.8
N.A.
53.8
57.4
N.A.
41.9
N.A.
24.2
23.1
N.A.
N.A.
Protein Similarity:
100
37.7
45.8
91.5
N.A.
84.4
83.7
N.A.
69.5
73.4
N.A.
60.1
N.A.
44.6
38.7
N.A.
N.A.
P-Site Identity:
100
0
6.6
0
N.A.
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
0
13.3
26.6
N.A.
26.6
13.3
N.A.
13.3
13.3
N.A.
13.3
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
22.7
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
43.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
8
8
8
8
0
0
24
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
16
16
8
8
0
0
8
0
0
0
8
16
0
8
% D
% Glu:
24
8
24
8
0
0
8
8
8
0
0
0
0
0
8
% E
% Phe:
8
0
0
8
8
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
16
8
8
8
8
8
24
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
16
0
0
8
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
16
16
0
16
24
24
0
8
0
24
8
16
24
% K
% Leu:
8
8
0
8
24
0
8
8
8
0
8
0
16
8
16
% L
% Met:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
0
0
16
16
8
0
0
16
0
8
0
0
0
8
% N
% Pro:
8
0
8
0
0
0
0
8
0
0
8
8
0
8
0
% P
% Gln:
0
8
16
0
0
8
8
0
8
0
8
0
0
8
0
% Q
% Arg:
0
8
0
0
8
16
0
0
8
24
16
0
8
8
8
% R
% Ser:
0
24
0
16
0
8
8
8
8
8
16
0
8
16
8
% S
% Thr:
8
8
0
8
0
0
0
8
0
0
16
31
16
8
0
% T
% Val:
0
8
8
0
8
16
0
0
8
16
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _