Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AASDH All Species: 4.85
Human Site: T750 Identified Species: 8.89
UniProt: Q4L235 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4L235 NP_861522.2 1098 122597 T750 E G K P A I G T Q K M E L H V
Chimpanzee Pan troglodytes XP_526619 419 46896 Y74 K D A S V K E Y I F K E L Q K
Rhesus Macaque Macaca mulatta XP_001084597 517 57678 R172 G D S L K S I R L L S E I E K
Dog Lupus familis XP_539278 1094 122201 A746 E G T Y G T A A K K M E L H V
Cat Felis silvestris
Mouse Mus musculus Q80WC9 1100 121551 M749 G S P V V G A M A M A L R E R
Rat Rattus norvegicus XP_344231 1099 121246 E748 R S P G T G A E P M V L R E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521114 1121 120374 G770 A G R R A G P G A L T L R V R
Chicken Gallus gallus XP_420697 1128 125269 T773 A E C S H V T T A D L A L R M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RG49 1149 125488 S782 H G G V R E D S T G V L P L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLL0 1012 113065 V667 K L Q I Y W K V N F E K C I D
Honey Bee Apis mellifera XP_395233 653 74131 Y308 Y V L W D D S Y H H L H L P D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002325887 1058 116913 V712 V V V K Q Q D V Y L F I G S H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198442 1040 115575 S694 M E S C V D A S P L V V L K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.4 44.9 85.4 N.A. 72.8 71.8 N.A. 53.8 57.4 N.A. 41.9 N.A. 24.2 23.1 N.A. N.A.
Protein Similarity: 100 37.7 45.8 91.5 N.A. 84.4 83.7 N.A. 69.5 73.4 N.A. 60.1 N.A. 44.6 38.7 N.A. N.A.
P-Site Identity: 100 13.3 6.6 53.3 N.A. 0 0 N.A. 13.3 13.3 N.A. 6.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 20 13.3 60 N.A. 0 6.6 N.A. 20 33.3 N.A. 20 N.A. 20 13.3 N.A. N.A.
Percent
Protein Identity: 22.7 N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: 43.1 N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 0 16 0 31 8 24 0 8 8 0 0 8 % A
% Cys: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 16 0 0 8 16 16 0 0 8 0 0 0 0 24 % D
% Glu: 16 16 0 0 0 8 8 8 0 0 8 31 0 24 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 16 8 0 0 0 0 % F
% Gly: 16 31 8 8 8 24 8 8 0 8 0 0 8 0 0 % G
% His: 8 0 0 0 8 0 0 0 8 8 0 8 0 16 8 % H
% Ile: 0 0 0 8 0 8 8 0 8 0 0 8 8 8 0 % I
% Lys: 16 0 8 8 8 8 8 0 8 16 8 8 0 8 16 % K
% Leu: 0 8 8 8 0 0 0 0 8 31 16 31 47 8 0 % L
% Met: 8 0 0 0 0 0 0 8 0 16 16 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 16 8 0 0 8 0 16 0 0 0 8 8 0 % P
% Gln: 0 0 8 0 8 8 0 0 8 0 0 0 0 8 0 % Q
% Arg: 8 0 8 8 8 0 0 8 0 0 0 0 24 8 24 % R
% Ser: 0 16 16 16 0 8 8 16 0 0 8 0 0 8 0 % S
% Thr: 0 0 8 0 8 8 8 16 8 0 8 0 0 0 0 % T
% Val: 8 16 8 16 24 8 0 16 0 0 24 8 0 8 16 % V
% Trp: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 8 0 0 16 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _