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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A6
All Species:
21.52
Human Site:
S58
Identified Species:
59.17
UniProt:
Q4U2R8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4U2R8
NP_004781.2
563
61816
S58
P
P
A
D
A
N
L
S
K
N
G
G
L
E
V
Chimpanzee
Pan troglodytes
XP_001160211
563
61784
S58
P
P
A
D
A
N
L
S
K
N
G
G
L
E
V
Rhesus Macaque
Macaca mulatta
XP_001115893
563
61601
S58
P
P
A
N
A
N
L
S
K
D
G
G
L
E
A
Dog
Lupus familis
XP_533258
550
60066
S58
P
P
A
N
A
N
L
S
T
D
G
E
L
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC69
545
59995
N56
C
R
P
P
A
N
A
N
L
S
K
D
G
G
L
Rat
Rattus norvegicus
O35956
551
60748
S58
P
P
A
N
A
N
L
S
K
D
G
G
L
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
S58
A
N
D
T
W
Y
Q
S
N
N
T
D
R
M
G
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
S58
P
H
A
N
L
S
M
S
S
T
D
A
V
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95R48
567
63148
S58
L
P
F
E
N
G
S
S
Y
D
L
P
T
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
89.5
N.A.
83.6
86.1
N.A.
N.A.
N.A.
50.9
50.4
N.A.
29.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.7
93.7
N.A.
90.7
92.1
N.A.
N.A.
N.A.
68.3
70.3
N.A.
51.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
66.6
N.A.
13.3
80
N.A.
N.A.
N.A.
13.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
33.3
93.3
N.A.
N.A.
N.A.
13.3
60
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
67
0
67
0
12
0
0
0
0
12
0
0
34
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
23
0
0
0
0
0
45
12
23
0
12
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
0
0
12
0
56
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
56
45
12
12
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
45
0
12
0
0
0
0
% K
% Leu:
12
0
0
0
12
0
56
0
12
0
12
0
56
0
23
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% M
% Asn:
0
12
0
45
12
67
0
12
12
34
0
0
0
0
0
% N
% Pro:
67
67
12
12
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
0
12
12
89
12
12
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
12
12
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
34
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _