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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM119
All Species:
8.48
Human Site:
S125
Identified Species:
31.11
UniProt:
Q4V9L6
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4V9L6
NP_859075.2
283
29203
S125
T
R
Q
K
Q
K
A
S
A
Y
Y
P
S
S
F
Chimpanzee
Pan troglodytes
XP_001164009
283
29268
S125
T
R
Q
K
H
K
A
S
A
Y
Y
P
S
S
F
Rhesus Macaque
Macaca mulatta
XP_001103263
280
29071
S125
T
R
Q
K
H
K
A
S
A
Y
Y
P
S
S
F
Dog
Lupus familis
XP_854479
281
28635
A125
R
Q
K
H
K
A
S
A
Y
Y
P
S
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R138
280
29382
P128
A
Y
Y
P
S
S
F
P
E
K
K
Y
V
D
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507888
300
31283
K128
P
S
S
F
P
K
K
K
Y
V
H
P
S
D
K
Chicken
Gallus gallus
XP_415183
235
24373
V94
Y
M
L
L
V
V
V
V
G
S
L
A
F
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.9
74.9
N.A.
68.5
N.A.
N.A.
50.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
95
81.6
N.A.
73.5
N.A.
N.A.
65.3
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
13.3
N.A.
0
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
46.6
N.A.
0
N.A.
N.A.
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
15
43
15
43
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% D
% Glu:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
15
0
0
0
0
0
15
15
43
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% G
% His:
0
0
0
15
29
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
43
15
58
15
15
0
15
15
0
0
0
15
% K
% Leu:
0
0
15
15
0
0
0
0
0
0
15
0
0
0
15
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
15
15
0
0
15
0
0
15
58
0
0
15
% P
% Gln:
0
15
43
0
15
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
15
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
15
0
15
15
15
43
0
15
0
15
72
43
0
% S
% Thr:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
15
15
15
15
0
15
0
0
15
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
15
15
0
0
0
0
0
29
58
43
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _