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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC58
All Species:
25.15
Human Site:
S66
Identified Species:
55.33
UniProt:
Q4VC31
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4VC31
NP_001017928.1
144
16620
S66
S
L
M
A
A
H
A
S
R
D
R
V
I
K
N
Chimpanzee
Pan troglodytes
XP_001166512
134
15592
I61
H
A
S
R
D
R
V
I
K
N
C
I
A
Q
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535759
188
21304
S110
S
L
R
E
A
H
A
S
R
D
R
V
I
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q6
144
16647
S66
S
L
M
A
A
H
V
S
R
D
R
V
I
K
N
Rat
Rattus norvegicus
NP_001099345
144
16672
S66
S
L
M
A
A
H
V
S
R
D
R
V
I
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416494
143
16478
S66
S
L
M
E
A
H
T
S
R
E
R
I
I
K
N
Frog
Xenopus laevis
Q6GPT7
144
16566
S66
S
L
Q
T
A
H
T
S
R
D
K
A
I
K
R
Zebra Danio
Brachydanio rerio
Q6PBK1
144
16351
S66
S
L
M
E
A
H
L
S
R
D
K
A
I
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730454
136
15789
R61
L
Q
E
S
H
L
A
R
Q
E
S
I
R
S
C
Honey Bee
Apis mellifera
XP_001121747
143
16573
T64
Q
I
Q
S
G
H
K
T
R
E
L
A
I
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782179
98
11287
N34
I
D
D
K
V
I
Y
N
L
N
K
V
V
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
N.A.
74.4
N.A.
96.5
98.6
N.A.
N.A.
76.3
75
76.3
N.A.
43.7
44.4
N.A.
39.5
Protein Similarity:
100
91.6
N.A.
75.5
N.A.
98.6
98.6
N.A.
N.A.
84
86.1
88.8
N.A.
65.2
63.8
N.A.
50.6
P-Site Identity:
100
0
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
73.3
60
66.6
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
66.6
80
N.A.
33.3
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
28
64
0
28
0
0
0
0
28
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
10
10
0
10
0
0
0
0
55
0
0
0
0
0
% D
% Glu:
0
0
10
28
0
0
0
0
0
28
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
10
73
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
0
10
0
0
0
28
73
0
0
% I
% Lys:
0
0
0
10
0
0
10
0
10
0
28
0
0
64
0
% K
% Leu:
10
64
0
0
0
10
10
0
10
0
10
0
0
0
0
% L
% Met:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
46
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
10
19
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
10
10
0
10
0
10
73
0
46
0
10
0
19
% R
% Ser:
64
0
10
19
0
0
0
64
0
0
10
0
0
10
10
% S
% Thr:
0
0
0
10
0
0
19
10
0
0
0
0
0
10
19
% T
% Val:
0
0
0
0
10
0
28
0
0
0
0
46
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _