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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP13A4 All Species: 30.3
Human Site: S735 Identified Species: 60.61
UniProt: Q4VNC1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4VNC1 NP_115655.2 1196 133973 S735 A R K S G M V S E S Q K V I L
Chimpanzee Pan troglodytes XP_516955 1196 134039 S735 A R K S G M V S E S Q K V I L
Rhesus Macaque Macaca mulatta XP_001086808 1184 131890 S735 A R K S G M V S E N Q K V I L
Dog Lupus familis XP_850465 1197 133945 S736 A R K S G M V S E S Q K V I L
Cat Felis silvestris
Mouse Mus musculus Q5XF90 1193 132785 S736 A R K S G M V S E G Q K V I L
Rat Rattus norvegicus XP_001053714 1204 133858 S747 A R K S G M V S E G Q K V I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512080 1148 128692 G718 I R T V M I T G D N L Q T A V
Chicken Gallus gallus Q5ZKB7 1204 134040 S732 A K N A G M I S P T N R V I L
Frog Xenopus laevis NP_001086889 1143 127992 T714 K I R S V M I T G D N L Q T A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27533 1256 140883 S767 I F V K Q S V S S S D E V I E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT02 1179 131097 S728 L I L G R S G S G N E Y K W V
Baker's Yeast Sacchar. cerevisiae Q12697 1472 166731 E1020 E E V E S N L E F L G F I I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.1 90.9 N.A. 87.1 84.9 N.A. 71.9 64.6 60.9 N.A. N.A. N.A. N.A. 33.5 N.A.
Protein Similarity: 100 99.7 95.3 95.1 N.A. 92.4 91 N.A. 82.6 78.3 73.3 N.A. N.A. N.A. N.A. 52.8 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 6.6 46.6 13.3 N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 40 80 33.3 N.A. N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 0 9 0 0 0 0 0 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 9 9 0 0 0 0 % D
% Glu: 9 9 0 9 0 0 0 9 50 0 9 9 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 9 0 0 9 0 0 9 % F
% Gly: 0 0 0 9 59 0 9 9 17 17 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 17 0 0 0 9 17 0 0 0 0 0 9 75 0 % I
% Lys: 9 9 50 9 0 0 0 0 0 0 0 50 9 0 0 % K
% Leu: 9 0 9 0 0 0 9 0 0 9 9 9 0 0 59 % L
% Met: 0 0 0 0 9 67 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 0 0 0 25 17 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 50 9 9 0 0 % Q
% Arg: 0 59 9 0 9 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 0 59 9 17 0 75 9 34 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 9 9 0 9 0 0 9 9 0 % T
% Val: 0 0 17 9 9 0 59 0 0 0 0 0 67 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _